Istituto degli Endotipi in Oncologia, Metabolismo e Immunologia "G. Salvatore" (IEOMI)
Progetti di ricerca
Progetti di ricerca di diretta responsabilità dell'Istituto
- Unravelling paradoxes in regulatory T cell biology: the molecular basis for an mTOR - dependent oscillatory metabolic switch controlling immune tolerance and autoimmunity (DSB.AD001.052)
- Unveiling the role of annexin A1 in Multiple Sclerosis: identification of an endogenous factor decoding T cell breach of the blood brain barrier and immune tolerance (DSB.AD001.054)
- IMMUNE CELLS ASSAY TO PREDICT C-PEPTIDE LOSS (DSB.AD001.056)
- Identificazione di vettori molecolari per la progettazione di sonde per l'Imaging diagnostico delle patologie oncologiche (DSB.AD001.065)
- Phosphomimetic-peptide technology targeting LTCCs: a new tool for modulating conditions of primary and post-inflammatory cardiomyopathy? (DSB.AD001.068)
- Meccanismi di regolazione cellulare e molecolare coinvolti nella proliferazione, nel differenziamento e nella trasformazione neoplastica (DSB.AD001.069)
- Basi metaboliche del controllo della tolleranza immunologica nella autoimmunità, nell'obesità e nell'infertilità (DSB.AD001.070)
- Extracellular microRNAs as molecular link between immune and metabolic dysregulation in Type 1 Diabetes (DSB.AD001.072)
- Unveiling the multifaceted activities of BG12 (dimethylfumarate) on immune tolerance through its action on the systemic immunometabolic asset and regulatory T cell functions (DSB.AD001.073)
- Unveiling the role of FoxP3 splicing variants in regulatory T cells (Tregs) from subjects with breast cancer (DSB.AD001.080)
- Phase I studies of LNA-i-miR-221 and LNA Gapmer 17-92 inhibitor in refractory multiple myeloma patients (DSB.AD001.081)
- Role of genetic polymorphism of the cladribine-apoptotic pathway on T cell metabolism and susceptibility to Multiple Sclerosis (DSB.AD001.089)
- EFSD CD3+CD56+ cells a novel human regulatory population: function and molecular mechanism in type 1 diabetes (DSB.AD001.091)
- AIRC IG grant 2017 - cod. 20095 - Development of a GRASP65/Aurora-A signalling network as a therapeutic target for cancer (DSB.AD001.107)
- AIRC LUINI 2018Dissecting and targeting the oncogenic molecular mechanism of action of Golph3, a regulator of Golgi traffic. (DSB.AD001.108)
- FISM call 2018 DE ROSA "RUOLO DELLE VESCICOLE EXTRACELLULARI NELLA REGOLAZIONE DELL'ESPRESSIONE DEL FOXP3 E DELLA FUNZIONE SOPPRESSORIA IN CELLULE T REGOLATORIE NELLA SCLEROSI MULTIPLA" (DSB.AD001.137)
- PRIN 2017-2017K7FSYB_004-DE ROSA "Stromal-immune cell crosstalk in the generation of tertiary lymphoid structure in solid cancers: immunometabolic aspects and implications for cancer therapy" (DSB.AD001.153)
- AIRC-IG Rif.230522019 CERCHIA "DEVELOPMENT of innovative drug-loaded and aptamer targeted nanosystem for treatment of triple-negative breast cancer (DSB.AD001.157)
- Contratto Dompè -Gene Profile -SHP1 (DSB.AD001.172)
- KAUST University - Computational identification of drugs inhibiting breast cancer stem cells by inducing differentiation (DSB.AD001.179)
- FISR2019_00374 -MEDYCA-Disregolazioni del metiloma in cancro: un approccio sinergico multidisciplinare per combatterle (MeDyCa) (DSB.AD001.183)
- OCRA Ovarian Cancer Research Alliance Grant Number:813369 "Exploiting PARP-modulating enzymes in ovarian cancer therapy" (DSB.AD001.196)
- Ricerca Finalizzata 2018 - Convenzione progetto GR-2018-12367517 - Titolo: Pharmacological targeting of CtBP1/BARS in cancer. (DSB.AD001.205)
- Impaired angiogenesis in Diabetes: unravelling the role of Glyoxalase 1 and methylglyoxal (DSB.AD003.020)
- MONTE TABOR Genomica del Diabete di tipo II (DSB.AD003.025)
- ELI LILLY ITALIA S.p.A. (DSB.AD003.047)
- AOU TORINO MIELE"Epigenetic and psychologic correlates of metabolic control in people with type 2 diabetes followed by a long-term structured self-management education program" (DSB.AD003.070)
- Cognitive dysfunction in dysmetabolic obesity and diabetes: role of inter-organic crosstalk and cellular ageing (DSB.AD003.083)
- H2020-MSCA-ITN-2019 G.A. N. 859962 -SECRET- "Exploitation of the SECRETory pathway for cancer therapy to address European research" (DSB.AD006.273)
- CONTRATTO BIOIMAGING CNR - DOMPE' FARMACEUTICI SPA (DSB.AD007.157)
- AIRC IG 2018 DE LUCA N. 21420 MICROSCOPIA CORRELATIVA PER L'IMAGING DEL CANCRO (DSB.AD008.489)
- PRIN - 2017 20177XJCHX_002 - Daniela CORDA INTEGRATION OF CUTTING-EDGE SPECTROSCOPIC AND IMAGING TECHNIQUES FOR THE STRUCTURAL ANALYSIS OF LIVING-CELL MACHINERIES FROM THE ATOMIC TO THE CELLULAR (DSB.AD008.566)
Altri progetti di ricerca a cui l'Istituto collabora
- Molecular and functional effects of methylglyoxal on human microvascular retinal cells (DSB.AD003.056)
- Extracellular vesicles from a natural source for tailormade nanomaterials' -- 'Ves4US' (DSB.AD008.439)
- Progetto Bandiera NANOMAX (DFM.AD005.058)
- POR CIRO (DSB.AD001.126)
- Attività di Coordinamento 2021-2023 (DSB.AD001.191)
- RECOVER-COVID19 (DSB.AD007.224)
- INCIPIT H2020 (DSB.AD008.158)
- Premiale TERABIO (DSB.AD008.370)
- INVECCHIAMENTO (DSB.AD009.001)
- EURO-BIOIMAGING (quota FOE 2019) (DSB.AD010.014)
- EURO-BIOIMAGING (quota FOE 2018) - previsto dalla Roadmap europea (DSB.AD010.019)