The scientific activities of the Institute are developed on the themes of modern research programs in three major areas:
1) Mechanisms of disease and Human genetics;
2) Development and Stem cell biolgy;
3) Molecular and Genetic approaches to fundamental biology.
Experimental systems are most diversified, from human samples to cell and mouse models. The IGB is concentrated to the study of human diseases and cancer.
Human diseases include Neurodegenerative and muscle diseases, autoimmune and cardiovascular diseases, Rett syndrome, Incontinentia Pigmenti, Retinal diseases and Imprinting defects including Russel-Beckwith syndrome and Neonatal Diabetes.