The Department of Biomedical Sciences manages the research activity in Biology, Medicine and Public Health. It provides technologies and services to both the public and the private area, with the purpose of promoting knowledge on the fundamental mechanism governing physiological and pathological aspects in living organism, starting from basic research in life sciences to the study of human diseases and of innovative therapeutic interventions. The ultimate aim is to explore new opportunities for ameliorating the health of mankind.
The fundamental activities regard oncology, neurodegenerative diseases, cardiovascular and pulmonary diseases, immunology and infectious diseases, epidemiology and health care research, Biology and biomedical technologies. In these areas, some technologies have been developed and they have found a wider use in the different benchmark areas: proteomics, pharmacogenomics, advanced calculus in bioinformatics and system biology, robotic systems for the limbs’ rehabilitation, molecular diagnostics and imaging.
Thanks to a 7000-year old ice core, the Idpa-Cnr and an international team have discovered that an alpine glacier is now accelerating due to atmospheric warming. The deepest part of the Mt. Ortles glacier (Eastern Italian Alps) has indeed started to move for the first time since the period of the Tyrolean Iceman. The study has been published in The Cryosphere
Dr Cosetta Bertoli, from MRC Laboratory for Molecular Cell Biology, University College London, United Kingdom, will give a seminar on oncogene-induced replication stress that is a crucial driver of genomic instability and one of the key events contributing to the onset of cancer
A preclinical study indicates a possible new therapy for medulloblastoma, the most common brain malignancy in childhood. The study, conducted by a group of researchers of the Institute of Cell Biology and Neurobiology of the National Research Council of Italy at the Santa Lucia Foundation in Rome, highlights the ability of chemokine Cxcl3 to completely inhibit the tumor. The research results are published in Frontiers in Pharmacology
Cnr-Isasi Researchers reveal an innovative possibility to identify sick cells in the blood stream, not visible by standard techniques. The result has been published in a Nature Publishing Group Journal Light: Science and Applications. The effectiveness of the technique has been demonstrated also for the recognition of possible oceans’ contaminants
The repertoire of gluten immuno-toxic peptides has been extensively characterized in children with Celiac Disease thanks to a collaboration between Australia and Italy.This study, using large gluten peptide library and blood samples from children with Celiac Disease after a wheat bread consumption, demonstrates that the T lymhocytes from young celiacs recognize the same gluten peptides as T cells from adults with Celiac Disease. These findings have important implication for either novel therapeutic strategies, and for prevention of this worldwide spreading disease
In a study performed by Isafom-Cnr, published on 'International Journal of Astrobiology', have been highlighted structural relationships between terrestrial microbialites – rocks by bacterial origin – and martian sediments not only at microscopic level, but also at macroscopic and mesoscopic ones
A new study, performed by the Institute of Neuroscience and the Institute of Clinical Physiology of CNR, shows the possibility to combat age-dependent cognitive decline and Alzheimer’s disease in elderly people with leisure, logical, motor and social activities. The study has been conducted in a new structure built in the CNR area of Pisa. The results have been published in 'Scientific Reports'