The Department of Biomedical Sciences manages the research activity in Biology, Medicine and Public Health. It provides technologies and services to both the public and the private area, with the purpose of promoting knowledge on the fundamental mechanism governing physiological and pathological aspects in living organism, starting from basic research in life sciences to the study of human diseases and of innovative therapeutic interventions. The ultimate aim is to explore new opportunities for ameliorating the health of mankind.
The fundamental activities regard oncology, neurodegenerative diseases, cardiovascular and pulmonary diseases, immunology and infectious diseases, epidemiology and health care research, Biology and biomedical technologies. In these areas, some technologies have been developed and they have found a wider use in the different benchmark areas: proteomics, pharmacogenomics, advanced calculus in bioinformatics and system biology, robotic systems for the limbs’ rehabilitation, molecular diagnostics and imaging.
A study published in the journal Pediatrics outlined the prospect of a new hereditary transmission mechanism of Incontinentia pigmenti disease. A team of researchers from the Institute of genetics and biophysics of Cnr of Naples with the Pediatric hospital Bambino Gesù and the University of Ferrara, discovered the novel forms of familiarity in Incontinentia pigmenti, by genetically characterizing the molecular alteration in somatic and germline cells of IP male father, although to date it was referring to the exclusive maternal inheritance
A research team at Isa-Cnr analyzed the use of these natural, antioxidant compounds in cancer, highlighting, in two studies, the pros and cons of their use and demonstrating that not always their effect(s) does depend upon the antioxidant activity. The articles have been published on Seminars in Cancer Biology and Oncotarget
Epilepsy and Intellectual Disability, which usually have their onset during childhood, are in some cases linked to mutations in the gene KIAA1202, which contains the information to produce the protein Shrm4. An international study, published on Nature Communication, coordinated by Maria Passafaro, at the Institute of Neuroscience of the National Research Council (IN-CNR), demonstrated one possible mechanism by which these mutations could cause those pathologies
Through sophisticated metagenomics and bioinformatics techniques, italian researchers from the Cnr - Italian Research Council - and University of Florence characterized the bacterial and fungal gut microbiota in a cohort of autistic individuals. The study, pulished on ‘Microbiome’, underlines the importance of the microbiome as biomarker and therapeutic target, in dietary intervention studies for the improvement of the quality of life of ASDs patients
A research study conducted at the Institute for Photonics and Nanotechnologies of the National Research Council has been published in the prestigious journal Nature Physics. An international team of scientists has monitored in real-time the scattering behavior of electrons propagating in a non-conducting material after the interaction with high-energy photons. Their insights could have an important impact for radiotherapy
Iom-Cnr and Sissa unveil new functional mechanisms of important pharmacological targets. The study has been published in the Journal of Physical Chemistry Letters
The 17th congress of the European society for photobiology will be held in Pisa (Italy) under the aegis of Cnr, Pisa Cnr Campus and Pisa University and municipality
Dr Nicola Normanno from the Istituto nazionale tumori 'Fondazione G. Pascale'-Ircss, Naples, will give a seminar on the molecular heterogeneity of colon cancer. The event is organized by Ibp-Cnr
A study published in the New England Journal of Medicine reports an important new mechanism of predisposition to two autoimmune diseases, multiple sclerosis (MS) and systemic lupus erythematosus (Lupus)
The EU-funded project Cupido, started in February 2017, proposes an innovative solution: the application of nanotechnologies to the cardiovascular field. Cupido aims to hit the core of the cardiovascular disease, developing inhalable nanoparticles that can deliver as simple as breathing a therapeutic directly to the diseased heart. Nanoparticles are extremely tiny, almost 1 million times smaller than a grain of sand in size and far too small to see with conventional microscopes
Full resolution of cognitive conflicts requires brain’s undivided attention. That's why conflicts are potentially dangerous in situations requiring sustained monitoring, such as, for instance, driving. This was revealed by a study carried out by the Institute of Bioimaging and Molecular Physiology of the National Research Council in collaboration with the University of Milan Bicocca
The repertoire of gluten immuno-toxic peptides has been extensively characterized in children with Celiac Disease thanks to a collaboration between Australia and Italy