Biomedical sciences

The Department of Biomedical Sciences manages the research activity in Biology, Medicine and Public Health. It provides technologies and services to both the public and the private area, with the purpose of promoting knowledge on the fundamental mechanism governing physiological and pathological aspects in living organism, starting from basic research in life sciences to the study of human diseases and of innovative therapeutic interventions. The ultimate aim is to explore new opportunities for ameliorating the health of mankind.

The fundamental activities regard oncology, neurodegenerative diseases, cardiovascular and pulmonary diseases, immunology and infectious diseases, epidemiology and health care research, Biology and biomedical technologies. In these areas, some technologies have been developed and they have found a wider use in the different benchmark areas: proteomics, pharmacogenomics, advanced calculus in bioinformatics and system biology, robotic systems for the limbs’ rehabilitation, molecular diagnostics and imaging. 

Download the Department brochure - Department video (Italian version).

A novel gene therapy approach for treating Parkinson's disease

Press release 07/09/2017

A new study has successfully established the first gene therapy approach to reduce or prevent a-synuclein toxic aggregates that are causing neuronal dysfunctions and loss in Parkinson’s disease. These results pave the way for testing gene therapy approaches for the treatment of neurodegenerative diseases that might affect also large brain areas. The study has been published in 'Molecular Therapy'

Incontinentia pigmenti: new research on genetic transmission

Press release 10/08/2017

A study published in the journal Pediatrics outlined the prospect of a new hereditary transmission mechanism of Incontinentia pigmenti disease. A team of researchers from the Institute of genetics and biophysics of Cnr of Naples with the Pediatric hospital Bambino Gesù and the University of Ferrara, discovered the novel forms of familiarity in Incontinentia pigmenti, by genetically characterizing the molecular alteration in somatic and germline cells of IP male father, although to date it was referring to the exclusive maternal inheritance

Polyphenols against cancer? A question to be investigated

Press release 13/06/2017

A research team at Isa-Cnr analyzed the use of these natural, antioxidant compounds in cancer, highlighting, in two studies, the pros and cons of their use and demonstrating that not always their effect(s) does depend upon the antioxidant activity. The articles have been published on Seminars in Cancer Biology and Oncotarget

Epilepsy and Intellectual Disability: a new molecular mechanism unravelled

Press release 15/05/2017

Epilepsy and Intellectual Disability, which usually have their onset during childhood, are in some cases linked to mutations in the gene KIAA1202, which contains the information to produce the protein Shrm4. An international study, published on Nature Communication, coordinated by Maria Passafaro, at the Institute of Neuroscience of the National Research Council (IN-CNR), demonstrated one possible mechanism by which these mutations could cause those pathologies

Gut microbiota, key element to understand autism

Press release 01/06/2017

Through sophisticated metagenomics and bioinformatics techniques, italian researchers from the Cnr - Italian Research Council - and University of Florence characterized the bacterial and fungal gut microbiota in a cohort of autistic individuals. The study, pulished on ‘Microbiome’, underlines the importance of the microbiome as biomarker and therapeutic target, in dietary intervention studies for the improvement of the quality of life of ASDs patients 

A stopwatch for electron motion inside matter

Press release 23/05/2017

A research study conducted at the Institute for Photonics and Nanotechnologies of the National Research Council has been published in the prestigious journal Nature Physics.  An international team of scientists has monitored in real-time the scattering behavior of electrons propagating in a non-conducting material after the interaction with high-energy photons. Their insights could have an important impact for radiotherapy

Towards more effective therapies to fight breast cancer

Press release 17/05/2017

Iom-Cnr and Sissa unveil new functional mechanisms of important pharmacological targets. The study has been published in the Journal of Physical Chemistry Letters

Signals, choices and conflicts: our brain unravels them by means of attention

Press release 04/05/2017

Full resolution of cognitive conflicts requires brain’s undivided attention. That's why conflicts are potentially dangerous in situations requiring sustained monitoring, such as, for instance, driving. This was revealed by a study carried out by the Institute of Bioimaging and Molecular Physiology of the National Research Council in collaboration with the University of Milan Bicocca