Research project

Electrofluidodynamics (DCM.AD006.126)

Thematic area

Chemical sciences and materials technology

Project area

Chimica e tecnologia dei materiali (DCM.AD006)

Structure responsible for the research project

Institute of Polymers, Composites and Biomaterials (IPCB)

Project manager

VINCENZO GUARINO
Phone number: 0039 0812425944
Email: vincenzo.guarino@cnr.it

Abstract

A large variety of processes and tools have recently emerged to design biomaterials with controlled chemical, physical, and biological properties for biomedical applications. Among them, electrofluidodynamics (EFDs) are revolutionizing traditional biomaterial manufacturing approaches by the use of electrostatic forces as driving force for the fabrication of 3D templates able to address cells and/or molecules both in vitro and in vivo. They basically identify relatively complex fabrication processes to design innovative devices--based on fibers and/or particles at micro- and/or submicrometric-size scale with restrained manufacturing costs but high functional complexity. In this project, the activities will be mainly focused on the optimization of different electrofluidodynamic processes, i.e., electrospinning, electrospraying, and electrodynamic atomization, and on the design and fabrication of bioinspired platforms for different biomedical uses (i.e., tissue engineering,drug delivery, nanomedicine).

Goals

The main scope of the project is to investigate the potential use of the large set of electrofluidodynamic processes, i.e., including electrospinning, electrospraying and electrodynamic atomization - for the development of active platforms for the evaluation of cell materials interaction and therapeutic treatments. This will be reached by the optimization study of main technological aspects of EFDTs, such as basic setup configuration and the role of process parameters. Moreover, a relevant topic is to identify and impart peculiar features to the devices as a function of the specific requirements of the biomedical application, i order to customize the device for different clinical uses (tissue repair and restoration, regenerative medicine, drug delivery, nanomedicine)

Start date of activity

11/04/2019

Keywords

Biomaterials,, Tissue engineering, Electrospinning

Last update: 06/07/2025