Research project

iPC Individualized Paediatric Cure (DIT.AD021.087)

Thematic area

Engineering, ICT and technologies for energy and transportation

Project area

Matematica Applicata (DIT.AD021)

Structure responsible for the research project

Institute for applied mathematics "Mauro Picone" (IAC)

Project manager

CHRISTINE NARDINI
Phone number: 0649937347
Email: c.nardini@iac.cnr.it

Abstract

Effective personalized medicine for paediatric cancers must address a multitude of challenges, including domain-specific challenges. To
overcome these challenges, we propose a comprehensive computational effort to combine knowledge-base, machine-learning, and
mechanistic models to predict optimal standard and experimental therapies for each child. Our approach is based on virtual patient
models-in-silico avatars whose analysis can inform personalized diagnostics and recommend treatments.

Goals

Our platform will also allow care
givers to query models and infer benefits and drawbacks for specific treatment combinations for each child.

Start date of activity

01/01/2019

Keywords

paediatric cancer, individualized therapy, virtual patients

Last update: 28/05/2024