Research project

Pupiltraits (3rd Party H2020 UNIPI) (DSB.AD004.274)

Thematic area

Biomedical sciences

Project area

Neuroscienze (DSB.AD004)

Structure responsible for the research project

Institute of neuroscience (IN)

Project manager

GUIDOMARCO CICCHINI
Phone number: 0506213185
Email: cicchini@in.cnr.it

Abstract

PUPILTRAITS will measure visual processing with both classic and new methods, including pupil responses, ultra-high field Magnetic Resonance of human visual cortex, and psychophysics. Based on solid pilot data, we predict that differences in behavioral and cortical properties co-vary with personality traits, providing new reliable biomarkers of the local context-independent perception associated with autistics traits, even in young children (using pupillometry). These tools will also reveal changes of perception within individuals: during a safe and simple physiological intervention (such as ketosis), to show that early visual processing can be altered by acting on metabolism, and that this consequently affects holistic/local perceptual styles.

Goals

The aim of the project is to provide new knowledge on the relationship between metabolism, cortical processing and perception. This has the potential for a strong societal impact: it can change our understanding of pervasive developmental disorders, like Autistic Spectrum Disorders, characterized by a different way of processing incoming information; it can aid their diagnosis through objective evaluation of perceptual styles, and encourage innovative therapeutic approaches aimed at changing perception and behavior by acting on general physiology: how we eat and exercise

Start date of activity

01/03/2019

Keywords

Biomarkers, Cortical vision

Last update: 22/05/2025