Research project

ImmunoSenescenza: cellule e molecole in funzione dell'età e dell'ambiente. (DSB.AD001.151)

Thematic area

Biomedical sciences

Project area

Oncologia e Immunologia (DSB.AD001)

Structure responsible for the research project

Institute for Genetic and Biomedical Research (IRGB)

Project manager

EDOARDO FIORILLO
Phone number: 0782480674
Email: edoardo.fiorillo@irgb.cnr.it

Abstract

The Project focusses on the discovery of the factors contributing to the variance of hundreds of traits of the immune system that will be referred as "Immunophenotypes". The diverse factors influencing the immune system considered were the genetics, the ageing, the sex, and environmental such as exposure to cigarette smoke.

Goals

The Project aims to quantify the age-related /life-long changes of the immune system in thousands of individuals, aged 18 to 110 years through the analysis of flow-sorted immune cell traits belonging to the innate and adaptive immunity that immunophenotypes through seven multicolor antibody panels.

Start date of activity

01/01/2020

Keywords

Immunosenescenza, Autoimmunità, Infiammazione

Last update: 17/09/2024