Research project

B2B - Modeling spontaneous Breast cancer metastasis TO the Bone with a first-of-its-kind 3D device that recapitulates physiological tissue-level complexity (DIT.AD010.031)

Thematic area

Engineering, ICT and technologies for energy and transportation

Project area

Biotecnologie (DIT.AD010)

Structure responsible for the research project

Institute of Electronics, Computer and Telecommunication Engineering (IEIIT)

Project manager

Phone number: 0106475213


Cancer patients developing a metastatic disease are considered incurable. Breast cancer hits 1
woman in 8, and itsmost common metastatic site is the bone. A major hurdle to overcome
breast cancer mortality is the lack of understanding of dynamics leading to the spread of
breast cancer cells to the bone. Consequently, metastasissuppressing agents have not been
found to date, neither as newly developed drugs nor as repurposing of existing ones.


gli obiettivi del porgetto B2B sono la realizzazione di una piattaforma sperimentale in vitro in grado di modellizzare la formazione spontanea di metastasi dal tumore alla mammella all'osso, atraverso tecncihe avanzate di sistemi microfluidici e bioprinting

Start date of activity




Last update: 11/12/2023