Morphology of the secretory pathway
Il 16/01/2014 ore 11.00 - 13.30
Sala Conferenze, CNR Via P. Castellino, 111
80131 Napoli
The aim of this 'mini course' is to provide participants with the opportunity to learn more about the mechanisms of the intracellular transport. The course will be starts with an introdution by Dr Alberto Luini (IBP, CNR, Naples). Speakers are:
Dr. Alexandre Mironov from IFOM-FIRC Institute of Molecular Oncology, Milan, Italy and Prof. Margit Pavelka from Center for Anatomy and Cell Biology, Department of Cell Biology and Ultrastrustructure Research, Vienna, Austria.
Russian scientist Alexandre Mironov became group leader at IFOM in 2010. His research program focus is models of intracellular transport within the within the Golgi apparatus and related aspects of tumorigenesis. At IFOM today, Alexandre Mironov, combines his varied expertise with cancer research. Believing in keeping things simple, his group is working on the development of a diagnostic test for prevention, based on the early detection of excessive double-strand RNA. Alexandre Mironov, who is often known to say 'it's always Golgi', has made major contributions on the functionality of the apparatus, publishing in Nature and Cell.
Prof Pavelka will talk about the Golgi apparatus and its organization in cell physiology and pathology based on insights from electron microscopy and tomography. In her work, particular attention is drawn to the Golgi apparatus architecture and dynamics influenced by endocytic traffic, drug treatments and cellular stress and the relationships of Golgi apparatus structure and function.
Prof Pavelka focused on medical histology and cell biology drawing particular attention to ultrastructure research and electron microscopic techniques, cytochemical methods and cryotechniques, including high pressure freezing and freeze-substitution; several years ago, with the new installation of a 200kV electron microscope in her department, she started with electron tomography and 3D-analyses.
Organizzato da:
IBP, CNR
Referente organizzativo:
Alberto Luini
CNR - Istituto di biochimica delle proteine
via P. Castellino, 111 80131 Napoli
a.luini@ibp.cnr.it
081/6132535
Modalità di accesso: ingresso libero
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