Glycans in health and disease from molecular mechanisms to biomedical applications
Il 24/02/2026 ore 14.30 - 16.30
Conference Room, Area della Ricerca NA1
via P. Castellino, 111, Naples
Glycans are key regulators of health and disease. This seminar will provide a broad overview of their roles, from fundamental molecular mechanisms to translational biomedical applications. As essential structural and informational molecules, carbohydrates play critical immunological and structural roles at interfaces such as the host-microbes interface and the tumor microenvironment.
The structural mimicry and immunological properties of pathogen-associated glycans make them ideal targets for vaccines design. I will discuss the rational development of carbohydrate-based vaccines, focusing on conjugate vaccine technology (a strategy proven highly successful against bacterial diseases like pneumonia and meningitis).
Finally, the seminar will explore the frontier of glycans research, including their roles in modulating the microbiome interactions with the host, their utility as biomarkers for cancer, and their function as modulators in the tumor microenvironment and other diseases.
By bridging fundamental glycoscience with applied research, deciphering and understanding the "glycan code" becomes essential for developing next-generation diagnostics, therapeutics, and prophylactics, translating molecular insights into improved human health outcomes.
Organizzato da:
Istituto di Biochimica e Biologia Cellulare
Referente organizzativo:
Maria Rosaria Coscia
Cnr-Ibbc
via P. Castellino, 111
Napoli
mariarosaria.coscia@ibbc.cnr.it
Modalità di accesso: ingresso libero
https://events.teams.microsoft.com/event/82a88f65-edc8-47fb-8761-2a6b35abd85a@34c64e9f-d27f-4edd-a1f0-1397f0c84f94
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