Structural organization of the Golgi apparatus

Il 15/07/2014 ore 14.30 - 15.30

Sala Conferenze CNR, Via P. Castellino 111 80131 Napoli

Prof Martin Lowe from University of Manchester, UK, will give a seminar on the structure and function of the Golgi apparatus. The Golgi apparatus lies at the heart of the secretory pathway where it modifies cargo proteins and sorts them to their final destinations, which can be inside or outside the cell. The Golgi apparatus has a very distinctive organization, comprising flattened membrane sacs called cisternae layered on top of each other to form stacks, which in vertebrates are further organized into a ribbon structure. How the Golgi maintains this organization and how Golgi structure relates to its function remain poorly understood. Prof Lowe's studies have focussed on the golgin family of coiled-coil proteins that have been implicated in linking, or tethering, of Golgi membranes. He will discuss our recent progress studying two members of this family, GMAP-210 and GM130, which play key structural and trafficking roles at the Golgi apparatus.

 

Organizzato da:
IBP, CNR

Referente organizzativo:
Antonino Colanzi
CNR - Istituto di biochimica delle proteine
Via P. Castellino, 111 Napoli
a.colanzi@ibp.cnr.it
081/6132538

Modalità di accesso: ingresso libero