"Molecular basis of how nerve agents & anti-Alzheimer drugs function:3D structure of Acetylcholinesterase"

Il 24/02/2014 ore 14.30 - 15.30

Sala Conferenze CNR, Via P. Castellino, 111 80131 Napoli

Professor Joel L. Sussman is the recipient of Morton & Gladys Pickman Chair in the Structural Biology Department of Structural Biology, Weizmann Institute of Science Rehovot, Israel. Together with Prof. Israel Silman (Neurobiology), he is studying the 3D structure/function of nervous system proteins, such as acetylcholinesterase (AChE), cholinesterase-like adhesion molecules (CLAMs), snake toxins, β-glucosidase, β-secretase & paraoxonase. The goal is to find new leads for treating neurological disorders, including Alzheimer's Disease and autism. He is also studying intrinsically unstructured proteins and how proteins adapt to extreme environments, e.g. halotolerant proteins. In parallel, he has helped to establish the Israel Structural Proteomics Center (ISPC), and the Jean Goldwurm 3D Visualization Theater, where it is possible to view 3D images of protein structures. He is also involved in the EC Forum for European Structural Proteomics (FESP).

Organizzato da:
IBP, CNR

Referente organizzativo:
Giuseppe Manco
CNR - Istituto di biochimica delle proteine
Via P. Castellino, 111 80131 Napoli
g.manco@ibp.cnr.it
081/6132296

Modalità di accesso: ingresso libero