PRIN 2017 - 2017CBHCWF - Luigi Ambrosio (DCM.AD007.096)
Area tematica
Scienze chimiche e tecnologie dei materiali
Area progettuale
Chimica e materiali per la salute e le scienze della vita (DCM.AD007)Struttura responsabile del progetto di ricerca
Istituto per i Polimeri, Compositi e Biomateriali (IPCB)
Altre strutture che collaborano al progetto di ricerca
Responsabile di progetto
LUIGI AMBROSIO
Telefono: +0812425929
E-mail: luigi.ambrosio@cnr.it
Abstract
SAPIENT will aim to elucidate the mechanical, structural, chemical and biological implications of collagen-glucose interactions over the full range of (patho-)physiological glucose concentrations. To this end,
we have assembled leading groups in the areas of materials science, polymer, medicine together with excellent tissue engineering facilities to generate relevant murine and human tissue analogues, and
mouse models. This partnership will deliver enhanced tools for investigating collagen-sugar interactions across molecular, fibril, engineered tissue matrix to ex vivo and in vitro models. The detail of the molecular, structural and biological interactions will be studied across length scales from atomic through nano and micro to macro, providing for the first time a comprehensive set of tools and more complete
understanding of glycation and their roles in the (patho-)physiology of animals and humans.
Data inizio attività
14/09/2019
Parole chiave
biomaterials, tissue engineering, bioprinting
Ultimo aggiornamento: 11/10/2024