Progetto di ricerca

iPC Individualized Paediatric Cure (DIT.AD021.087)

Area tematica

Ingegneria, ICT e tecnologie per l'energia e i trasporti

Area progettuale

Matematica Applicata (DIT.AD021)

Struttura responsabile del progetto di ricerca

Istituto per le applicazioni del calcolo "Mauro Picone" (IAC)

Responsabile di progetto

CHRISTINE NARDINI
Telefono: 0649937347
E-mail: c.nardini@iac.cnr.it

Abstract

Effective personalized medicine for paediatric cancers must address a multitude of challenges, including domain-specific challenges. To
overcome these challenges, we propose a comprehensive computational effort to combine knowledge-base, machine-learning, and
mechanistic models to predict optimal standard and experimental therapies for each child. Our approach is based on virtual patient
models-in-silico avatars whose analysis can inform personalized diagnostics and recommend treatments.

Obiettivi

Our platform will also allow care
givers to query models and infer benefits and drawbacks for specific treatment combinations for each child.

Data inizio attività

01/01/2019

Parole chiave

paediatric cancer, individualized therapy, virtual patients

Ultimo aggiornamento: 22/06/2024