Mitochondrial poly(ADP-ribosylation): from old data to new perspectives. (Articolo in rivista)

Type
Label
  • Mitochondrial poly(ADP-ribosylation): from old data to new perspectives. (Articolo in rivista) (literal)
Anno
  • 2004-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1096/fj.04-1841rev (literal)
Alternative label
  • Scovassi AI. (2004)
    Mitochondrial poly(ADP-ribosylation): from old data to new perspectives.
    in The FASEB journal
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Scovassi AI. (literal)
Pagina inizio
  • 1487 (literal)
Pagina fine
  • 1488 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#altreInformazioni
  • CORRESPONDING AUTHOR Citazioni fino al 2011: 28 Quartile Q1 Categoria A - BIOCHEMISTRY & MOLECULAR BIOLOGY B - BIOLOGY C - CELL BIOLOGY IF: 6.82 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 18 (literal)
Rivista
Note
  • Scopus (literal)
  • ISI Web of Science (WOS) (literal)
  • PubMe (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • IGM-CNR (literal)
Titolo
  • Mitochondrial poly(ADP-ribosylation): from old data to new perspectives. (literal)
Abstract
  • Poly(ADP-ribosylation) is involved in DNA repair and replication, transcription, and cell death. For a long time, only one poly(ADP-ribosylating) enzyme was known, named ADPRT/PARP (EC 2.4.2.30). The recent discovery of a family of PARPs has provided a high degree of complexity in the field. Moreover, the finding that poly(ADP-ribosylation) is not confined to the nucleus but is also carried out by cytoplasmic enzymes supports the idea that it could regulate proteins localized in different cellular compartments. In this respect, a reappraisal of the literature on mitochondrial poly(ADP-ribosylation) could be useful, as well as a discussion of its relevance regarding the current \"hot\" view of poly(ADP-ribosylation) as a mediator of cell death. (literal)
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