The role of 3-dimethylaminopropylamine and amidoamine in contact allergy to cocamidopropylbetaine (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• The role of 3-dimethylaminopropylamine and amidoamine in contact allergy to cocamidopropylbetaine (Articolo in rivista) (literal)

Anno

• 2003-01-01T00:00:00+01:00 (literal)

Alternative label

• FOTI C., BONAMONTE D., MASCOLO G., CORCELLI A., LOBASSO S., RIGANO L., ANGELINI G. (2003)
  The role of 3-dimethylaminopropylamine and amidoamine in contact allergy to cocamidopropylbetaine
  in Contact dermatitis
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• FOTI C., BONAMONTE D., MASCOLO G., CORCELLI A., LOBASSO S., RIGANO L., ANGELINI G. (literal)

Pagina inizio

• 194 (literal)

Pagina fine

• 198 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 48 (literal)

Rivista

• Contact dermatitis (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 4 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Università di Bari, CNR-IRSA (literal)

Titolo

• The role of 3-dimethylaminopropylamine and amidoamine in contact allergy to cocamidopropylbetaine (literal)

Abstract

• Since it has been found that all subjects with contact allergy to cocamidopropylbetaine (CAPB) have positive reactions to 3-dimetylaminopropylamine (DMAPA), and reports have appeared in literature of the sensitizing action of amidoamine in products containing CAPB, we aimed to verify the possibility that pure amidoamine may have a sensitizing role in subjects with positive reactions to CAPB. To this end, in 10 patients with contact allergy to a commercial CAPB, we tested DMAPA 1% aq. and a pure amidoamine in concentrations ranging from 0.5% aq. to 0.1% aq. The study showed that all patients with positive reactions to DMAPA reacted to amidoamine at 0.5% and 0.25% aq., while 4 of the 10 also had positive reactions to amidoamine at 0.1% aq. We consider that simultaneous allergic reaction to DMAPA and amidoamine represents cross-reactivity and hypotesize that DMAPA is in fact the true sensitizing substance, while amidoamine, which may in any case release DMAPA in vivo as a result of enzymatic hydrolysis, may favour the transepidermal penetration of the sensitizing agent. In addition, we advise that testing of CAPB be suspended, because, as suggested by chemico-structural analyses and demonstrated in vivo, when thoroughly purified, it no longer has a sensitizing action. (literal)

Prodotto di

• Water research institute (IRSA) (Istituto)

Autore CNR

• GIUSEPPE MASCOLO (Persona)

Incoming links:

Prodotto

• Water research institute (IRSA) (Istituto)

Autore CNR di

• GIUSEPPE MASCOLO (Persona)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Contact dermatitis (Rivista)