A Numerical Study to Compare Stimulations by Intraoperative Microelectrodes and Chronic Macroelectrodes in the DBS Technique (Articolo in rivista)

Type
Label
  • A Numerical Study to Compare Stimulations by Intraoperative Microelectrodes and Chronic Macroelectrodes in the DBS Technique (Articolo in rivista) (literal)
Anno
  • 2013-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1155/2013/262739 (literal)
Alternative label
  • Paffi A., Apollonio F., Puxeddu M. G., Parazzini M., d'Inzeo G., Ravazzani P., Liberti M. (2013)
    A Numerical Study to Compare Stimulations by Intraoperative Microelectrodes and Chronic Macroelectrodes in the DBS Technique
    in BioMed Research International [electronic resource]
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Paffi A., Apollonio F., Puxeddu M. G., Parazzini M., d'Inzeo G., Ravazzani P., Liberti M. (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#altreInformazioni
  • Article ID 262739, 7 pages (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url
  • http://www.hindawi.com/journals/bmri/2013/262739/ (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 2013 (literal)
Rivista
Note
  • ISI Web of Science (WOS) (literal)
  • Scopu (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Paffi A.: Department of Information Engineering, Electronics and Telecommunication, Sapienza University of Rome, and Italian Inter-University Center for the Study of Electromagnetic Fields and Biological Systems (ICEmB), Genova, Italy Apollonio F.: Department of Information Engineering, Electronics and Telecommunication, Sapienza University of Rome, and Italian Inter-University Center for the Study of Electromagnetic Fields and Biological Systems (ICEmB), Genova, Italy Puxeddu M. G.: Department of Information Engineering, Electronics and Telecommunication, Sapienza University of Rome, Italy Parazzini M.: CNR Consiglio Nazionale delle Ricerche, Istituto di Elettronica e di Ingegneria dell'Informazione e delle Telecomunicazioni IEIIT, Milano, Italy d'Inzeo G.: Department of Information Engineering, Electronics and Telecommunication, Sapienza University of Rome, and Italian Inter-University Center for the Study of Electromagnetic Fields and Biological Systems (ICEmB), Genova, Italy Ravazzani P.: CNR Consiglio Nazionale delle Ricerche, Istituto di Elettronica e di Ingegneria dell'Informazione e delle Telecomunicazioni IEIIT, Milano, Italy Liberti M.: Department of Information Engineering, Electronics and Telecommunication, Sapienza University of Rome, and Italian Inter-University Center for the Study of Electromagnetic Fields and Biological Systems (ICEmB), Genova, Italy (literal)
Titolo
  • A Numerical Study to Compare Stimulations by Intraoperative Microelectrodes and Chronic Macroelectrodes in the DBS Technique (literal)
Abstract
  • Deep brain stimulation is a clinical technique for the treatment of parkinson's disease based on the electric stimulation, through an implanted electrode, of specific basal ganglia in the brain. To identify the correct target of stimulation and to choose the optimal parameters for the stimulating signal, intraoperative microelectrodes are generally used. However, when they are replaced with the chronic macroelectrode, the effect of the stimulation is often very different. Here, we used numerical simulations to predict the stimulation of neuronal fibers induced by microelectrodes and macroelectrodes placed in different positions with respect to each other. Results indicate that comparable stimulations can be obtained if the chronic macroelectrode is correctly positioned with the same electric center of the intraoperative microelectrode. Otherwise, some groups of fibers may experience a completely different electric stimulation. (literal)
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