Consiglio Nazionale delle Ricerche

Tipo di prodottoArticolo in rivista
TitoloInterindividual Variability in Functional Connectivity as Long-Term Correlate of Temporal Discounting
Anno di pubblicazione2015
FormatoCartaceo
Autore/iCalluso, Cinzia; Tosoni, Annalisa; Pezzulo, Giovanni; Spadone, Sara; Committeri, Giorgia
Affiliazioni autoriISTC-CNR
Autori CNR e affiliazioni
  • GIOVANNI PEZZULO
Lingua/e
  • inglese
AbstractDuring intertemporal choice (IT) future outcomes are usually devaluated as a function of the delay, a phenomenon known as temporal discounting (TD). Based on task-evoked activity, previous neuroimaging studies have described several networks associated with TD. However, given its relevance for several disorders, a critical challenge is to define a specific neural marker able to predict TD independently of task execution. To this aim, we used resting-state functional connectivity MRI (fcMRI) and measured TD during economic choices several months apart in 25 human subjects. We further explored the relationship between TD, impulsivity and decision uncertainty by collecting standard questionnaires on individual trait/state differences. Our findings indicate that fcMRI within and between critical nodes of task-evoked neural networks associated with TD correlates with discounting behavior measured a long time afterwards, independently of impulsivity. Importantly, the nodes form an intrinsic circuit that might support all the mechanisms underlying TD, from the representation of subjective value to choice selection through modulatory effects of cognitive control and episodic prospection.
Lingua abstractinglese
Altro abstract-
Lingua altro abstract-
Pagine da-
Pagine a-
Pagine totali22
RivistaPloS one
Attiva dal 2006
Editore: Public Library of Science - San Francisco, CA
Paese di pubblicazione: Stati Uniti d'America
Lingua: inglese
ISSN: 1932-6203
Titolo chiave: PloS one
Titolo proprio: PloS one
Titolo abbreviato: PLoS ONE
Titoli alternativi:
  • Public Library of Science one
  • PLoS 1
Numero volume della rivista10
Fascicolo della rivista3
DOI10.1371/journal.pone.0119710
Verificato da referee-
Stato della pubblicazionePublished version
Indicizzazione (in banche dati controllate)
  • ISI Web of Science (WOS) (Codice:000351183500113)
Parole chiavedecision making, discounting
Link (URL, URI)-
Titolo parallelo-
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Data di accettazione-
Note/Altre informazioni-
Strutture CNR
  • ISTC — Istituto di scienze e tecnologie della cognizione
Moduli/Attività/Sottoprogetti CNR
  • SV.P16.008.001 : Computational Embodied Neuroscience
Progetti Europei
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