Consiglio Nazionale delle Ricerche

IVAN MERELLI

BETA
The information published in this page are entirely managed by IVAN MERELLI who is completely responsible for it.

Ivan Merelli is currently staff scientist at the Institute for Biomedical Technologies (ITB) of the Italian National Research Council (CNR). In December 2003 he received a MSc in Biomedical Engineering from the Politecnico di Milano and in February 2009 a PhD in Computer Science from the University of Milano - Bicocca. His research activities concern the bioinformatic analysis and integration of multi-omic datasets (bulk RNA-seq, scRNA-seq, bulk ATAC-seq, scATAC-seq, ChIP-seq, GUIDE-seq, BAR-seq, RRBS, WGBS, WES, WGS, Hi-C) and more generally the management and development of infrastructures for treating data produced using high throughput technologies of molecular biology. He is the coauthor of more than eighty papers published in international peer-reviewed journals and more than eighty contributions in International Conference Proceedings.

Interest areas:

Bioinformatics, Computational Biology, Systems Biology, Multi-omics data analysis and integration, Gene Therapy, Genome Editing, High-Performance Computing, Big Data Analytics, Machine Learning


International Ids


H-indexes

Google Scholar H-Index: 23
Scopus H-Index: 19
ISI-WoS H-Index: 17

Education

Dottorato in Informatica
Università degli Studi di Milano-Bicocca - piazza della Sienza 1, Milano
Graduation date: 2009-02-09
Attendance time period: 01/2006 - 12/2008
Thesis: Image based surface analysis oriented to macromolecular functional annotation and interaction screening

Ingegneria Biomedica
Politecnico di Milano - piazza Leonardo da Vinci 33, Milano
Grade: 90/100
Graduation date: 2003-12-19
Attendance time period: 09/1997 - 09/2003
Thesis: Analisi e modellizzazione di superfici proteiche per l'identificazione di determinanti funzionali


Research activities classification (ERC)

COMPUTER SCIENCE AND INFORMATICS: INFORMATICS AND INFORMATION SYSTEMS, COMPUTER SCIENCE, SCIENTIFIC COMPUTING, INTELLIGENT SYSTEMS
GENETICS, GENOMICS, BIOINFORMATICS AND SYSTEMS BIOLOGY: GENETICS, POPULATION GENETICS, MOLECULAR GENETICS, GENOMICS, TRANSCRIPTOMICS, PROTEOMICS, METABOLOMICS, BIOINFORMATICS, COMPUTATIONAL BIOLOGY, BIOSTATISTICS, BIOLOGICAL MODELLING AND SIMULATION, SYSTEMS BIOLOGY, GENETIC EPIDEMIOLOGY
LIFE SCIENCES
PHYSICAL SCIENCES AND ENGINEERING

Research products

D. D'Agostino, P. Liò, M. Aldinucci, and I. Merelli

+ Advantages of using graph databases to explore chromatin conformation capture experiments.

(2021) in BMC bioinformatics
Marcovecchio, Genni Enza; Ferrua, Francesca; Fontana, Elena; Beretta, Stefano; Genua, Marco; Bortolomai, Ileana; Conti, Anastasia; Montin, Davide; Cascarano, Maria Teresa; Bergante, Sonia; D'Oria, Veronica; Giamberti, Alessandro; Amodio, Donato; Cancrini, Caterina; Carotti, Adriano; Di Micco, Raffaella; Merelli, Ivan; Bosticardo, Marita; Villa, Anna

+ Premature Senescence and Increased Oxidative Stress in the Thymus of Down Syndrome Patients

(2021) in Frontiers in immunology
Vavassori, Valentina; Mercuri, Elisabetta; Marcovecchio, Genni E.; Castiello, Maria C.; Schiroli, Giulia; Albano, Luisa; Margulies, Carrie; Buquicchio, Frank; Fontana, Elena; Beretta, Stefano; Merelli, Ivan; Cappelleri, Andrea; Rancoita, Paola M.V.; Lougaris, Vassilios; Plebani, Alessandro; Kanariou, Maria; Lankester, Arjan; Ferrua, Francesca; Scanziani, Eugenio; Cotta-Ramusino, Cecilia; Villa, Anna; Naldini, Luigi; Genovese, Pietro

+ Modeling, optimization, and comparable efficacy of T cell and hematopoietic stem cell gene editing for treating hyper-IgM syndrome

(2021) in EMBO molecular medicine (Print)
Ferrari, Samuele; Beretta, Stefano; Jacob, Aurelien; Cittaro, Davide; Albano, Luisa; Merelli, Ivan; Naldini, Luigi; Genovese, Pietro

+ BAR-Seq clonal tracking of gene-edited cells

(2021) in Nature protocols (Print)
Mucci, Adele; Antonarelli, Gabriele; Caserta, Carolina; Vittoria, Francesco Maria; Desantis, Giacomo; Pagani, Riccardo; Greco, Beatrice; Casucci, Monica; Escobar, Giulia; Passerini, Laura; Lachmann, Nico; Sanvito, Francesca; Barcella, Matteo; Merelli, Ivan; Naldini, Luigi; Gentner, Bernhard

+ Myeloid cell-based delivery of IFN-? reprograms the leukemia microenvironment and induces anti-tumoral immune responses

(2021) in EMBO molecular medicine (Print)
Capo, Valentina; Penna, Sara; Merelli, Ivan; Barcella, Matteo; Scala, Serena; Basso-Ricci, Luca; Draghici, Elena; Palagano, Eleonora; Zonari, Erika; Desantis, Giacomo; Uva, Paolo; Cusano, Roberto; Sergi, Lucia Sergi; Crisafulli, Laura; Moshous, Despina; Stepensky, Polina; Drabko, Katarzyna; Kaya, Zühre; Unal, Ekrem; Gezdiric, Alper; Menna, Giuseppe; Serafini, Marta; Aiuti, Alessandro; Locatelli, Silvia Laura; Carlo-Stella, Carmelo; Schulz, Ansgar S.; Ficara, Francesca; Sobacchi, Cristina; Gentner, Bernhard; Villa, Anna

+ Expanded circulating hematopoietic stem/ progenitor cells as novel cell source for the treatment of TCIRG1 osteopetrosis

(2021) in Haematologica (Roma)
Cazzaniga, Paolo; Raposo, Maria; Besozzi, Daniela; Merelli, Ivan; Staiano, Antonino; Ciaramella, Angelo; Rizzo, Riccardo; Manzoni, Luca

+ Selected papers from the 15th and 16th international conference on Computational Intelligence Methods for Bioinformatics and Biostatistics

(2021) in BMC bioinformatics
Signorelli, Paola; Pivari, Francesca; Barcella, Matteo; Merelli, Ivan; Zulueta, Aida; Dei Cas, Michele; Rosso, Lorenzo; Ghidoni, Riccardo; Caretti, Anna; Paroni, Rita; Mingione, Alessandra

+ Myriocin modulates the altered lipid metabolism and storage in cystic fibrosis

(2021) in Cellular signalling
D. D'Agostino, I. Merelli, M. Aldinucci, and D. Cesini

+ Hardware and Software Solutions for Energy-Efficient Computing in Scientific Programming

(2021) in Scientific programming
Biavasco, Riccardo; Lettera, Emanuele; Giannetti, Kety; Gilioli, Diego; Beretta, Stefano; Conti, Anastasia; Scala, Serena; Cesana, Daniela; Gallina, Pierangela; Norelli, Margherita; Basso-Ricci, Luca; Bondanza, Attilio; Cavalli, Giulio; Ponzoni, Maurilio; Dagna, Lorenzo; Doglioni, Claudio; Aiuti, Alessandro; Merelli, Ivan; Di Micco, Raffaella; Montini, Eugenio

+ Oncogene-induced senescence in hematopoietic progenitors features myeloid restricted hematopoiesis, chronic inflammation and histiocytosis

(2021) in Nature communications
See all