Profilo personale

Silvia Mandillo

Le informazioni pubblicate in questa pagina sono gestite in completa autonomia da SILVIA MANDILLO il/la quale se ne assume ogni responsabilità

She graduated in Natural Sciences at Universita' La Sapienza- Roma in 1995 with a thesis in Psychobiology, then she obtained her PhD in Psychology at Tufts University, Medford-Boston, USA in 2001. During Graduate School at Tufts University she worked as Research Assistant and Primate Facility manager in the Psychopharmacology Lab (1996-1998) and Nutrition Lab (1998-2001) of the Psychology Dept. From 2001 to 2002 she was a Postdoctoral fellow at Psychobiology Lab, Dept. of Genetics and Molecular Biology at Universita' La Sapienza Roma.

Since 2003 she is Research Scientist at CNR Institute of Cell Biology (2003-2010) and Institute of Cell Biology and Neurobiology (2011-present). Since 2004 she is faculty at Universita' di Roma La Sapienza, Master in Neurobiology, courses of 'Techniques for the study of animal behavior' and 'Methods in Behavioral Neuroscience'. In 2013 she obtained the Abilitazione Scientifica Nazionale a Professore Associato.

Her research focuses on the study of motor and cognitive functions as well as social and emotional behaviors by using automated systems and ethologically based direct behavioral observations. She is currently conducting in-depth behavioral analysis of inbred and mutant mouse strains to develop genetic models of neurodegenerative and psychiatric diseases, e.g. Parkinson's Disease, Amyotrophic Lateral Sclerosis, Schizophrenia, Autism Spectrum Disorders, anxiety and depression.

Aree di interesse:

Psychobiology, Behavioral Pharmacology, Models of Drug Abuse, Neurodegenerative and Psychiatric Diseases, Learning and Memory, Behavioural Neurobiology, Mouse Phenotyping, Animal Welfare, Statistical analysis.


Contatti

Telefono: +39-06-90091410/205
Pec: silvia.mandillo@postecert.it

Identificatori Internazionali

Scopus Author ID: 6603484229
WoS Researcher ID: E-6503-2019
Research Gate: Silvia_Mandillo
Google Scholar: iuT0jBUAAAAJ&hl=en

H-index

Google Scholar H-Index: 22
ISI-WoS H-Index: 20

Prodotti della ricerca

Golini E 1, Rigamonti M 2, Iannello F 2, De Rosa C 1, Scavizzi F 1, Raspa M 1, Mandillo S 1

A non-invasive digital biomarker for the detection of rest disturbances in the SOD1G93A mouse model of ALS

(2020) in Frontiers in neuroscience (Online)
Silvia Mandillo

DVC technology to detect digital biomarkers in a mouse model of ALS

(2020) Accelerating animal model research by leveraging home cage monitoring, Webinar Tecniplast - Mary Ann Liebert Inc. Publishers, 22/04/2020
Elisabetta Golini1, Mara Rigamonti2, Fabio Iannello2, Carla De Rosa1, Ferdinando Scavizzi1, Marcello Raspa1, Silvia Mandillo1

A non-invasive digital biomarker for the detection of rest disturbances in the SOD1G93A mouse model of ALS

(2019) in bioRxiv the preprint server for biology
Provenzano C.[1], Cardinali B.[1], Perfetti A.[2], Mandillo S.[1], Golini E.[1], Strimpakos G.[1], Voellenkle C.[2], Longo M.[2], Martelli F.[2], Falcone G. [1]

GENE EDITING IN MYOTONIC DYSTROPHY TYPE 1: ASSESSMENT OF EFFICIENCY, SAFETY AND THERAPEUTIC EFFECT OF CTG-REPEAT DELETION IN A MOUSE MODEL OF DISEASE

(2019) XX Scientific Convention Telethon, Riva del Garda (TN), 28-30/10/2019
Silvia Mandillo

New phenotyping developments: Home cage analysis

(2019) INFRAFRONTIER/IMPC Conference 2019, Helsinki, Finlandia, 3-5/6/2019
Silvia Mandillo

Home cage monitoring, re-cap and discussion

(2019) Knockout Mouse Phenotyping Project (KOMP2) & International Mouse Phenotyping Consortium (IMPC) 2019 Annual Fall Meeting, Rockville, MD (USA), 17-19/11/2019
Bret A. Moore1, Brian C. Leonard2, Lionel Sebbag1, Sydney G. Edwards1, Ann Cooper1, Denise M. Imai3, 4, Luis Santos4, Christopher Reilly3, Stephen M. Griffey3, Lynette Bower5, David Clary5, 6, Michel J. Roux 7,8,9,10,11, Hamid Meziane7,8,9,10,11, Ewan Straiton Jeremy Mason Yann Herault Ann M. Flenniken12,14, Lauryl M.J. Nutter12,13, Zorana Berberovic12,14, Celeste Owen12,14, Susan Newbigging12,14, Hibret Adissu12,14, Mohammed Eskandarian12,14, Chih-Wei Hsu15, Sowmya Kalaga15, Uchechukwu Udensi15, Chinwe Asomugha15, Ritu Bohat16, Juan J. Gallegos16, John R. Seavitt16, Jason D. Heaney16, Arthur L. Beaudet16, Mary E. Dickinson15,16, Monica J. Justice12,13,16, Vivek Philip17, Vivek Kumar 17, Karen L. Svenson17, Robert E. Braun17, Sara Wells4, Heather Cater4, Michelle Stewart4, Sharon Clementson-Mobbs4, Russell Joynson4, Xiang Gao18, Tomohiro Suzuki19, Shigeharu Wakana 19, Damian Smedley20, J. K Seong21, Glauco Tocchini-Valentini22, Mark Moore23, Colin Fletcher24, Natasha Karp25, Ramiro Ram...

Identification of genes required for eye development by high-throughput screening of mouse knockouts

Bret A. Moore1, Brian C. Leonard2, Lionel Sebbag1, Sydney G. Edwards1, Ann Cooper1, Denise M. Imai3, 4, Luis Santos4, Christopher Reilly3, Stephen M. Griffey3, Lynette Bower5, David Clary5, 6, Michel J. Roux 7,8,9,10,11, Hamid Meziane7,8,9,10,11, Ewan Straiton Jeremy Mason Yann Herault Ann M. Flenniken12,14, Lauryl M.J. Nutter12,13, Zorana Berberovic12,14, Celeste Owen12,14, Susan Newbigging12,14, Hibret Adissu12,14, Mohammed Eskandarian12,14, Chih-Wei Hsu15, Sowmya Kalaga15, Uchechukwu Udensi15, Chinwe Asomugha15, Ritu Bohat16, Juan J. Gallegos16, John R. Seavitt16, Jason D. Heaney16, Arthur L. Beaudet16, Mary E. Dickinson15,16, Monica J. Justice12,13,16, Vivek Philip17, Vivek Kumar 17, Karen L. Svenson17, Robert E. Braun17, Sara Wells4, Heather Cater4, Michelle Stewart4, Sharon Clementson-Mobbs4, (2018) in Communications biology
Garbugino, Luciana; Golini, Elisabetta; Giuliani, Alessandro; Mandillo, Silvia

Prolonged Voluntary Running Negatively Affects Survival and Disease Prognosis of Male SOD1G93A Low-Copy Transgenic Mice

(2018) in Frontiers in behavioral neuroscience
Bitetti, Angelo; Mallory, Allison C.; Golini, Elisabetta; Carrieri, Claudia; Gutierrez, Hector Carreno; Perlas, Emerald; Perez-Rico, Yuvia A.; Tocchini-Valentini, Glauco P.; Enright, Anton J.; Norton, William H. J.; Mandillo, Silvia; O'Carroll, Donal; Shkumatava, Alena

MicroRNA degradation by a conserved target RNA regulates animal behavior

(2018) in Nature structural & molecular biology
Rozman J.; Rathkolb B.; Oestereicher M.A.; Schutt C.; Ravindranath A.C.; Leuchtenberger S.; Sharma S.; Kistler M.; Willershauser M.; Brommage R.; Meehan T.F.; Mason J.; Haselimashhadi H.; Aguilar-Pimentel A.; Becker L.; Treise I.; Moreth K.; Garrett L.; Holter S.M.; Zimprich A.; Marschall S.; Amarie O.V.; Calzada-Wack J.; Neff F.; Brachthauser L.; Lengger C.; Stoeger C.; Zapf L.; Cho Y.-L.; Da Silva-Buttkus P.; Kraiger M.J.; Mayer-Kuckuk P.; Gampe K.K.; Wu M.; Conte N.; Warren J.; Chen C.-K.; Tudose I.; Relac M.; Matthews P.; Cater H.L.; Natukunda H.P.; Cleak J.; Teboul L.M.; Clementson-Mobbs S.; Szoke-Kovacs Z.; Walling A.P.; Johnson S.J.; Codner G.F.; Fiegel T.; Ring N.; Westerberg H.; Greenaway S.; Sneddon D.; Morgan H.; Loeffler J.; Stewart M.E.; Ramirez-Solis R.; Bradley A.; Skarnes W.C.; Steel K.P.; Maguire S.A.; Dench J.; Lafont D.; Vancollie V.E.; Pearson S.A.; Gates A.S.; Sanderson M.; Shannon C.; Anthony L.F.E.; Sumowski M.T.; McLaren R.S.B.; Doe B.; Wardle-Jones H.; Griffith...

Identification of genetic elements in metabolism by high-throughput mouse phenotyping

(2018) in Nature communications
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