Profilo personale

Ivan Merelli

Le informazioni pubblicate in questa pagina sono gestite in completa autonomia da IVAN MERELLI il/la quale se ne assume ogni responsabilità

Ivan Merelli is currently staff scientist at the Institute for Biomedical Technologies (ITB) of the Italian National Research Council (CNR). In December 2003 he received a MSc in Biomedical Engineering from the Politecnico di Milano and in February 2009 a PhD in Computer Science from the University of Milano - Bicocca. His research activities concern the bioinformatic analysis and integration of multi-omic datasets (bulk RNA-seq, scRNA-seq, bulk ATAC-seq, scATAC-seq, ChIP-seq, GUIDE-seq, BAR-seq, RRBS, WGBS, WES, WGS, Hi-C) and more generally the management and development of infrastructures for treating data produced using high throughput technologies of molecular biology. He is the coauthor of more than eighty papers published in international peer-reviewed journals and more than eighty contributions in International Conference Proceedings.

Aree di interesse:

Bioinformatics, Computational Biology, Systems Biology, Multi-omic datasets analysis and integration, Gene Therapy, Genome Editing, High-Performance Computing, Big Data Analytics, Machine Learning


Identificatori Internazionali


H-index

Google Scholar H-Index: 23
Scopus H-Index: 19
ISI-WoS H-Index: 17

Formazione

Dottorato in Informatica
Dottorato
Università degli Studi di Milano-Bicocca - piazza della Sienza 1, Milano
Area disciplinare: INF/01
Data conseguimento: 2009-02-09
Frequenza: 01/2006 - 12/2008
Tesi: Image based surface analysis oriented to macromolecular functional annotation and interaction screening

Ingegneria Biomedica
Laurea (Vecchio Ordinamento)
Politecnico di Milano - piazza Leonardo da Vinci 33, Milano
Area disciplinare: 26
Votazione: 90/100
Data conseguimento: 2003-12-19
Frequenza: 09/1997 - 09/2003
Tesi: Analisi e modellizzazione di superfici proteiche per l'identificazione di determinanti funzionali


Competenze

BIOINFORMATICS AND STATISTICAL ANALYSIS OF GENOMIC DATA
BIOLOGICAL DATA INTEGRATION
GRID AND CLOUD COMPUTING
HIGH PERFORMANCE COMPUTING

Research activities classification (ERC)

COMPUTER SCIENCE AND INFORMATICS: INFORMATICS AND INFORMATION SYSTEMS, COMPUTER SCIENCE, SCIENTIFIC COMPUTING, INTELLIGENT SYSTEMS
GENETICS, GENOMICS, BIOINFORMATICS AND SYSTEMS BIOLOGY: GENETICS, POPULATION GENETICS, MOLECULAR GENETICS, GENOMICS, TRANSCRIPTOMICS, PROTEOMICS, METABOLOMICS, BIOINFORMATICS, COMPUTATIONAL BIOLOGY, BIOSTATISTICS, BIOLOGICAL MODELLING AND SIMULATION, SYSTEMS BIOLOGY, GENETIC EPIDEMIOLOGY
LIFE SCIENCES
PHYSICAL SCIENCES AND ENGINEERING

Classificazione attività di ricerca (ATECO)

PRODUZIONE DI SOFTWARE, CONSULENZA INFORMATICA E ATTIVITÀ CONNESSE
SERVIZI DI INFORMAZIONE E COMUNICAZIONE

Prodotti della ricerca

D. D'Agostino, P. Liò, M. Aldinucci, and I. Merelli

Advantages of using graph databases to explore chromatin conformation capture experiments.

(2021) in BMC bioinformatics
Marcovecchio, Genni Enza; Ferrua, Francesca; Fontana, Elena; Beretta, Stefano; Genua, Marco; Bortolomai, Ileana; Conti, Anastasia; Montin, Davide; Cascarano, Maria Teresa; Bergante, Sonia; D'Oria, Veronica; Giamberti, Alessandro; Amodio, Donato; Cancrini, Caterina; Carotti, Adriano; Di Micco, Raffaella; Merelli, Ivan; Bosticardo, Marita; Villa, Anna

Premature Senescence and Increased Oxidative Stress in the Thymus of Down Syndrome Patients

(2021) in Frontiers in immunology
Vavassori, Valentina; Mercuri, Elisabetta; Marcovecchio, Genni E.; Castiello, Maria C.; Schiroli, Giulia; Albano, Luisa; Margulies, Carrie; Buquicchio, Frank; Fontana, Elena; Beretta, Stefano; Merelli, Ivan; Cappelleri, Andrea; Rancoita, Paola M.V.; Lougaris, Vassilios; Plebani, Alessandro; Kanariou, Maria; Lankester, Arjan; Ferrua, Francesca; Scanziani, Eugenio; Cotta-Ramusino, Cecilia; Villa, Anna; Naldini, Luigi; Genovese, Pietro

Modeling, optimization, and comparable efficacy of T cell and hematopoietic stem cell gene editing for treating hyper-IgM syndrome

(2021) in EMBO molecular medicine (Print)
Ferrari, Samuele; Beretta, Stefano; Jacob, Aurelien; Cittaro, Davide; Albano, Luisa; Merelli, Ivan; Naldini, Luigi; Genovese, Pietro

BAR-Seq clonal tracking of gene-edited cells

(2021) in Nature protocols (Print)
Mucci, Adele; Antonarelli, Gabriele; Caserta, Carolina; Vittoria, Francesco Maria; Desantis, Giacomo; Pagani, Riccardo; Greco, Beatrice; Casucci, Monica; Escobar, Giulia; Passerini, Laura; Lachmann, Nico; Sanvito, Francesca; Barcella, Matteo; Merelli, Ivan; Naldini, Luigi; Gentner, Bernhard

Myeloid cell-based delivery of IFN-? reprograms the leukemia microenvironment and induces anti-tumoral immune responses

(2021) in EMBO molecular medicine (Print)
Capo, Valentina; Penna, Sara; Merelli, Ivan; Barcella, Matteo; Scala, Serena; Basso-Ricci, Luca; Draghici, Elena; Palagano, Eleonora; Zonari, Erika; Desantis, Giacomo; Uva, Paolo; Cusano, Roberto; Sergi, Lucia Sergi; Crisafulli, Laura; Moshous, Despina; Stepensky, Polina; Drabko, Katarzyna; Kaya, Zühre; Unal, Ekrem; Gezdiric, Alper; Menna, Giuseppe; Serafini, Marta; Aiuti, Alessandro; Locatelli, Silvia Laura; Carlo-Stella, Carmelo; Schulz, Ansgar S.; Ficara, Francesca; Sobacchi, Cristina; Gentner, Bernhard; Villa, Anna

Expanded circulating hematopoietic stem/ progenitor cells as novel cell source for the treatment of TCIRG1 osteopetrosis

(2021) in Haematologica (Roma)
Cazzaniga, Paolo; Raposo, Maria; Besozzi, Daniela; Merelli, Ivan; Staiano, Antonino; Ciaramella, Angelo; Rizzo, Riccardo; Manzoni, Luca

Selected papers from the 15th and 16th international conference on Computational Intelligence Methods for Bioinformatics and Biostatistics

(2021) in BMC bioinformatics
Signorelli, Paola; Pivari, Francesca; Barcella, Matteo; Merelli, Ivan; Zulueta, Aida; Dei Cas, Michele; Rosso, Lorenzo; Ghidoni, Riccardo; Caretti, Anna; Paroni, Rita; Mingione, Alessandra

Myriocin modulates the altered lipid metabolism and storage in cystic fibrosis

(2021) in Cellular signalling
D. D'Agostino, I. Merelli, M. Aldinucci, and D. Cesini

Hardware and Software Solutions for Energy-Efficient Computing in Scientific Programming

(2021) in Scientific programming
Biavasco, Riccardo; Lettera, Emanuele; Giannetti, Kety; Gilioli, Diego; Beretta, Stefano; Conti, Anastasia; Scala, Serena; Cesana, Daniela; Gallina, Pierangela; Norelli, Margherita; Basso-Ricci, Luca; Bondanza, Attilio; Cavalli, Giulio; Ponzoni, Maurilio; Dagna, Lorenzo; Doglioni, Claudio; Aiuti, Alessandro; Merelli, Ivan; Di Micco, Raffaella; Montini, Eugenio

Oncogene-induced senescence in hematopoietic progenitors features myeloid restricted hematopoiesis, chronic inflammation and histiocytosis

(2021) in Nature communications
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