Optical Fiber Device for Simultaneous Manometry, pH-metry and Bilimetry in Oesophagus (OPTIMO) (DIT.AD010.027)
Project areaBiotecnologie (DIT.AD010)
Structure responsible for the research project
The target of the present proposal is the design, implementation and characterization of a portable device based on a fully optical technology capable to perform simultaneously oesophageal manometry, pH-metry and bilimetry. It will provide physicians a compact and reliable tool to perform exhaustive diagnosis in gastroesophageal reflux pathologies. Pressure measurement along the oesophagus is perfomed by using an array of optical fibre gratings which ensures the monitoring along a length of about 30 cm with high spatial resolution. The sensors for the measurement of pH and bile are based on the change of absorption caused by the parameter under investigation. In the case of pH, an acid-base indicator which changes its absorption as a function of pH, is immobilized on controlled pore glasses suitable coupled to plastic optical fibres. As for bile detection, the measurement is based on the direct absorption of bilirubin, the main biliary pigment. Clinical assessment of the realized device on patients is scheduled in the last year of the project.
Start date of activity
Sensore Ottico, Pressione, Bile, pH, GERD
Last update: 05/12/2023