Consiglio Nazionale delle Ricerche

Tipo di prodottoArticolo in rivista
TitoloForecasting the performance status of head and neck cancer patient treatment by an interval arithmetic, pruned perceptron
Anno di pubblicazione2002
Formato-
Autore/iDrago, GP; Setti, E; Licitra, L; Liberati, D
Affiliazioni autoriPolitecn Milan; CNR; Ist Nazl Studio & Cura Tumori
Autori CNR e affiliazioni
  • DIEGO LIBERATI
Lingua/e
  • inglese
AbstractThe integration of chemotherapy and radiotherapy for the treatment of advanced head and neck cancer is still a matter of clinical investigation. An important limitation is that the concomitant administration of chemotherapy and radiotherapy still induces severe toxicity. In this paper, a simple artificial neural network is used to predict, on the basis of biological and clinical data, if the cumulative toxicity of the combined chemo-radiation treatment itself would be tolerated. The resulting method, tested on clinical data from a phase II trial, proved to be able to forecast which patients will tolerate a combined chemo-radiotherapeutic approach. This result should open a new perspective in the clinical approach, by supplying a potential predictive indicator for toxicity.
Lingua abstractinglese
Altro abstract-
Lingua altro abstract-
Pagine da782
Pagine a787
Pagine totali6
RivistaIEEE transactions on biomedical engineering (Print)
Attiva dal 1964
Editore: Institute of Electrical and Electronics Engineers, - New York, N.Y.
Paese di pubblicazione: Stati Uniti d'America
Lingua: inglese
ISSN: 0018-9294
Titolo chiave: IEEE transactions on biomedical engineering (Print)
Titolo proprio: IEEE transactions on bio-medical engineering (Print)
Titolo abbreviato: IEEE trans. biomed. eng. (Print)
Titoli alternativi:
  • Institute of Electrical and Electronics Engineers transactions on bio-medical engineering (Print)
  • IEEE transactions on biomedical engineering (Print)
  • Transactions on bio-medical engineering (Print)
Numero volume della rivista49
Fascicolo della rivista8
DOI10.1109/TBME.2002.800788
Verificato da refereeSì: Internazionale
Stato della pubblicazionePublished version
Indicizzazione (in banche dati controllate)
  • ISI Web of Science (WOS) (Codice:000176909100004)
Parole chiavechemo-radiation, head and neck cancer, interval arithmetic, learning, neural networks, perceptrons, performance status, predictive factors, toxicity
Link (URL, URI)-
Titolo parallelo-
Data di accettazione-
Note/Altre informazioni-
Strutture CNR
  • IEIIT — Istituto di elettronica e di ingegneria dell'informazione e delle telecomunicazioni
Moduli/Attività/Sottoprogetti CNR
  • DIT.AD007.007.004 : ICSB - Information and Control for Systems Biology
Progetti Europei-
Allegati