Consiglio Nazionale delle Ricerche

Tipo di prodottoAbstract in atti di convegno
TitoloDeep transcranial magnetic stimulation for the addiction treatment: Electric field distribution modelling
Anno di pubblicazione2018
FormatoElettronico
Autore/iSerena Fiocchi1, Emma Chiaramello1, Marta Parazzini1, Ileana Terruzzi2, Livio Luzi3,4, Paolo Ravazzani1
Affiliazioni autori1CNR Consiglio Nazionale delle Ricerche, Istituto di Elettronica e di Ingegneria dell'Informazione e delle Telecomunicazioni IEIIT, Milan, Italy 2Division of Metabolic and Cardiovascular Science, Metabolism, Nutrigenomics and Cellular Differentiation Unit, San Raffaele Scientific Institute, Milan, Italy 3Department of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy 4Endocrinology and Metabolic Diseases Unit, San Donato Hospital, Milan, Italy
Autori CNR e affiliazioni
  • SERENA FIOCCHI
  • EMMA CHIARAMELLO
  • PAOLO GIUSEPPE RAVAZZANI
  • MARTA PARAZZINI
Lingua/e
  • inglese
AbstractDeep Transcranial Magnetic Stimulation (dTMS) is a relatively new technique for brain stimulation that has been recently adopted in the treatment of different kind of addictions, including alcohol, cocaine, nicotine addiction and, in a broad sense, obesity or food addiction (for a review on the clinical use of dTMS coils see [1]). The complex dTMS coils (also named Hesed(H)-coils) [2-3] tridimensional structure allows indeed to reach even the deep targets of the brain whose impairment is strictly linked to the progression of those disorders, thus enhancing and enlarging the effect of the stimulation with respect to the extremely focal and superficial traditional TMS systems. In order to precisely characterize their efficacy, the knowledge of the induced electric field distribution in those targets is the first step to be taken. In this work we hence quantified, by means of computational techniques, both electric field distribution (E) and related parameters, such as focusing power and penetration depth, induced by a specific H-coil (named H4), precisely designed for the addiction treatment. Results (Fig. 1) show that H4 coil is able to induce peak of the induced E over the cingulate cortex and to follow on the insula and on the prefrontal cortex. Moreover, it can induce in the deepest tissues (i.e. nucleus accumbens, ipotalamus and ventral tegmental area) peak E levels ranging between the 20-55% of the maximum in the cortex (Emax) and it can penetrate the prefrontal cortex up to 4 cm with a E> 50% Emax, thus noticeably reducing the decrease with depth of the traditional TMS coils.
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Verificato da refereeSì: Internazionale
Stato della pubblicazionePublished version
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Parole chiavedeep TMS, transcranial magnetic stimulation, computational modelling
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Titolo convegno/congresso2nd IEEE Conference on Advances in Magnetics
Luogo convegno/congressoLa Thuille (AO)
Data/e convegno/congresso04/02/2018, 07/02/2018
RilevanzaInternazionale
RelazioneContributo
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Strutture CNR
  • IEIIT — Istituto di elettronica e di ingegneria dell'informazione e delle telecomunicazioni
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Allegati
  • Fiocchi_abstract AIM2018