Consiglio Nazionale delle Ricerche

Tipo di prodottoArticolo in rivista
TitoloModeling Pathological Hemodynamic Responses to the Valsalva Maneuver
Anno di pubblicazione2017
FormatoElettronico
Autore/iPstras, Leszek; Thomaseth, Karl; Waniewski, Jacek; Balzani, Italo; Bellavere, Federico
Affiliazioni autoriPolish Acad Sci; IEIIT-CNR; St Antonio Hosp; Rizzola Fdn Hosp
Autori CNR e affiliazioni
  • KARL THOMASETH
Lingua/e
  • inglese
AbstractThe Valsalva maneuver (VM) consisting in a forced expiration against closed airways is one of the most popular clinical tests of the autonomic nervous system function. When properly performed by a healthy subject, it features four characteristic phases of arterial blood pressure (BP) and heart rate (HR) variations, based on the magnitude of which the autonomic function may be assessed qualitatively and quantitatively. In patients with some disorders or in healthy patients subject to specific conditions, the pattern of BP and HR changes during the execution of the Valsalva maneuver may, however, differ from the typical sinusoidal-like pattern. Several types of such abnormal responses are well known and correspond to specific physiological conditions. In this paper, we use our earlier mathematical model of the cardiovascular response to the Valsalva maneuver to show that such pathological responses may be simulated by changing individual model parameters with a clear physiological meaning. The simulation results confirm the adaptability of our model and its usefulness for diagnostic or educational purposes.
Lingua abstractinglese
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Pagine totali9
RivistaJournal of biomechanical engineering
Attiva dal 1977
Editore: American Society of Mechanical Engineers, - [New York, N.Y.]
Paese di pubblicazione: Stati Uniti d'America
Lingua: inglese
ISSN: 0148-0731
Titolo chiave: Journal of biomechanical engineering
Titolo proprio: Journal of biomechanical engineering.
Titolo abbreviato: J. biomech. eng.
Numero volume della rivista139
Fascicolo della rivista6
DOI10.1115/1.4036258
Verificato da refereeSì: Internazionale
Stato della pubblicazionePublished version
Indicizzazione (in banche dati controllate)
  • ISI Web of Science (WOS) (Codice:000400901600001)
Parole chiavebaroreflex, autonomic function, blood pressure, heart rate variations, hemodynamics
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Strutture CNR
  • IEIIT — Istituto di elettronica e di ingegneria dell'informazione e delle telecomunicazioni
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