Consiglio Nazionale delle Ricerche

Tipo di prodottoArticolo in rivista
TitoloElectric field estimation of deep transcranial magnetic stimulation clinically used for the treatment of neuropsychiatric disorders in anatomical head models
Anno di pubblicazione2017
FormatoElettronico
Autore/iMarta Parazzini, Serena Fiocchi, Emma Chiaramello, Yiftach Roth, Abraham Zangen, Paolo Ravazzani
Affiliazioni autoriParazzini M., Fiocchi S., Chiaramello E., Ravazzani P.: Consiglio Nazionale delle Ricerche - Istituto di Elettronica e di Ingegneria dell'Informazione e delle Telecomunicazioni, Piazza Leonardo da Vinci 32 - 20133 Milano, Italy zangen A., Roth Y.: Department of Life Sciences, Ben-Gurion University of the Negev, Be'er Sheva, Israel
Autori CNR e affiliazioni
  • SERENA FIOCCHI
  • EMMA CHIARAMELLO
  • PAOLO GIUSEPPE RAVAZZANI
  • MARTA PARAZZINI
Lingua/e
  • inglese
AbstractLiterature studies showed the ability to treat neuropsychiatric disorders using H1 coil, developed for the deep Transcranial Magnetic Stimulation (dTMS). Despite the positive results of the clinical studies, the electric field (E) distributions inside the brain induced by this coil when it is positioned on the scalp according to the clinical studies themselves are not yet precisely estimated. This study aims to character- ize the E distributions due to the H1 coil in the brain of two realistic human models by computational electromagnetic techniques and to compare them with the ones due to the figure-of-8 coil, traditionally used in TMS and positioned as such to simulate the clinical experiments. Despite inter-individual differences, our results show that the dorsolateral prefrontal cortex is the region preferentially stimulated by both H1 and figure-of-8 coil when they are placed in the position on the scalp according to the clinical studies, with a more broad and non-focal distribution in the case of H1 coil. Moreover, the H1 coil spreads more than the figure-of-8 coil both in the prefrontal cortex and medial prefrontal cortex and towards some deeper brain structures and it is characterized by a higher penetration depth in the frontal lobe. This work highlights the importance of the knowledge of the electric field distribution in the brain tissues to interpret the outcomes of the experimental studies and to optimize the treatments.
Lingua abstractinglese
Altro abstract-
Lingua altro abstract-
Pagine da30
Pagine a38
Pagine totali-
RivistaMedical engineering & physics
Attiva dal 1994
Editore: Butterworth-Heinemann, - Oxford
Paese di pubblicazione: Regno Unito
Lingua: inglese
ISSN: 1350-4533
Titolo chiave: Medical engineering & physics
Titolo proprio: Medical engineering & physics.
Titolo abbreviato: Med. eng. phys.
Titolo alternativo: Medical engineering and physics
Numero volume della rivista43
Fascicolo della rivista-
DOI10.1016/j.medengphy.2017.02.003
Verificato da refereeSì: Internazionale
Stato della pubblicazionePublished version
Indicizzazione (in banche dati controllate)
  • Scopus (Codice:2-s2.0-85013469040)
  • ISI Web of Science (WOS) (Codice:000400213600003)
  • PubMed (Codice:28236602)
Parole chiaveDeep transcranial magnetic stimulation; Computational modeling High-resolution head modeling Neuropsychiatric disorders
Link (URL, URI)http://www.medengphys.com/action/doSearch?searchType=quick&searchText=chiaramello&occurrences=author&journalCode=jjbe&searchScope=fullSite
Titolo parallelo-
Data di accettazione05/02/2017
Note/Altre informazioni-
Strutture CNR
  • IEIIT — Istituto di elettronica e di ingegneria dell'informazione e delle telecomunicazioni
Moduli CNR-
Progetti Europei-
Allegati
PDF Version of the paper (documento privato )
Tipo documento: application/pdf