Consiglio Nazionale delle Ricerche

Tipo di prodottoArticolo in rivista
TitoloCoffee and tea consumption and risk of leukaemia in an adult population: A reanalysis of the Italian multicentre case-control study
Anno di pubblicazione2017
Autore/iStefano Parodi, Domenico Franco Merlo, Emanuele Stagnaro
Affiliazioni autoriInstitute of Electronics, Computer and Telecommunication Engineering, National Research Council of Italy, Genoa, Italy Unit of Clinical Trials, IRCCS San Martino-IST, Genoa, Italy Liguria Mortality Registry, IRCCS AOU San Martino-IST National Cancer Research Institute, Largo Rosanna Benzi, 10, 16132 Genoa, Italy
Autori CNR e affiliazioni
  • inglese
AbstractBackground: Coffee and tea are the most frequently consumed beverages in the world. Their potential effect on the risk of developing different types of malignancies has been largely investigated, but studies on leukaemia in adults are scarce. Methods: The present investigation is aimed at evaluating the potential role of regular coffee and tea intake on the risk of adult leukaemia by reanalysing a large population based case-control study carried out in Italy, a country with a high coffee consumption and a low use of green tea. Interviewed subjects, recruited between 1990 and 1993 in 11 Italian areas, included 1771 controls and 651 leukaemia cases. Association between Acute Myeloid Leukaemia (AML), Acute Lymphoid Leukaemia, Chronic Myeloid Leukaemia, Chronic Lymphoid Leukaemia, and use of coffee and tea was evaluated by standard logistic regression. Odds Ratios (OR) were estimated adjusting for the following potential confounders: gender, age, residence area, smoking habit, educational level, previous chemotherapy treatment, alcohol consumption and exposure to electromagnetic fields, radiation, pesticides and aromatic hydrocarbons. Results: No association was observed between regular use of coffee and any type of leukaemia. A small protective effect of tea intake was found among myeloid malignancies, which was more evident among AML (OR = 0.68, 95%CI: 0.49-0.94). However, no clear dose-response relation was found. Conclusion: The lower risk of leukaemia among regular coffee consumers, reported by a few of previous small studies, was not confirmed. The protective effect of tea on the AML risk is only partly consistent with results from other investigations.
Lingua abstractinglese
Altro abstract-
Lingua altro abstract-
Pagine da81
Pagine a87
Pagine totali7
RivistaCancer epidemiology (Online)
Attiva dal 2009
Editore: Elsevier Science - Amsterdam
Paese di pubblicazione: Paesi Bassi
Lingua: inglese
ISSN: 1877-783X
Titolo chiave: Cancer epidemiology (Online)
Titolo proprio: Cancer epidemiology. (Online)
Numero volume della rivista47
Fascicolo della rivista4
Verificato da refereeSì: Internazionale
Stato della pubblicazionePreprint
Indicizzazione (in banche dati controllate)-
Parole chiaveadult leukaemia; lymphoid malignancies; myeloid malignancies; tea; coffee; case-control study.
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Strutture CNR
  • IEIIT — Istituto di elettronica e di ingegneria dell'informazione e delle telecomunicazioni
Moduli CNR-
Progetti Europei-