Consiglio Nazionale delle Ricerche

Tipo di prodottoArticolo in rivista
TitoloIntracorporeal Glucose Disposal During Hemodialysis After a Standardized Glucose Load
Anno di pubblicazione2010
Formato-
Autore/iSchneditz, D.; Hafner-Giessauf, H.; Holzer, H.; Thomaseth, K.
Affiliazioni autori1: Institute of Physiology, Department of Internal Medicine, Medical University of Graz, Austria / 2, 3: Division of Nephrology, Department of Internal Medicine, Medical University of Graz, Austria / 4: Institute of Biomedical Engineering, Italian National Research Council, Padova, Italy
Autori CNR e affiliazioni
  • KARL THOMASETH
Lingua/e-
AbstractThe aim of this study was to quantify intracorporeal clearance and disposal of glucose after the administration of a standardized glucose load during regular hemodialysis done in stable and non-diabetic patients and to account for effects of extracorporeal clearance. A standardized load of glucose was administered approximately 30 min after starting hemodialysis with a constant dialysate glucose of 5.0 +/- 0.2 mmol/L. Glucose in the arterial line blood and in dialysate outflow was measured at baseline and in short intervals for a period of 1 h after the infusion. Tests were repeated within 1 week. Nine patients completed the study. Extracorporeal blood and dialysate flows were 304 +/- 34 and 500 mL/min, respectively. The intracorporeal clearance of glucose was 327 +/- 137 mL/min and 69.1 +/- 9.4% of total glucose clearance. Mass balance assessed from dialysate samples showed that 60.1 +/- 10.5% of glucose injected was disposed intracorporeally. The fraction of intracorporeal clearance and the fraction of intracorporeal glucose disposal were highly correlated (r = 0.94, p < 0.0001). The fraction of glucose disposed in hemodialysis patients can be determined from the amount of glucose injected and from the amount of glucose removed extracorporeally during hemodialysis without blood sampling. This measure could be of interest in surveillance of glucose control in hemodialysis patients.
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Pagine totali-
RivistaASAIO journal (1992)
Attiva dal 1992
Editore: Published for the Society by J.B. Lippincott Co., - Hagerstown, MD
Paese di pubblicazione: Stati Uniti d'America
Lingua: inglese
ISSN: 1058-2916
Titolo chiave: ASAIO journal (1992)
Titolo proprio: ASAIO journal : (1992)
Titolo abbreviato: ASAIO j. (1992)
Titoli alternativi:
  • Peer reviewed journal of the American Society for Artificial Internal Organs (1992)
  • American Society for Artificial Internal Organs journal (1992)
Numero volume della rivista-
Fascicolo della rivista-
DOI10.1097/MAT.0b013e3181ce1c9b
Verificato da refereeSì: Internazionale
Stato della pubblicazione-
Indicizzazione (in banche dati controllate)
  • ISI Web of Science (WOS) (Codice:000277655900009)
  • Scopus (Codice:2-s2.0-77951992405)
Parole chiaveBlood sampling, Diabetic patient, Dialysates, Glucose control, Hemodialysis patient
Link (URL, URI)http://www.ncbi.nlm.nih.gov/pubmed/20168210
Titolo parallelo-
Data di accettazione-
Note/Altre informazioni-
Strutture CNR
  • IEIIT — Istituto di elettronica e di ingegneria dell'informazione e delle telecomunicazioni
  • ISIB — Istituto di ingegneria biomedica
Moduli CNR
    Progetti Europei-
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      Rivista ISIASAIO JOURNAL [09919J0]
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