Consiglio Nazionale delle Ricerche

Tipo di prodottoArticolo in rivista
TitoloPotential health impacts of residential exposures to extremely low frequency magnetic fields in Europe
Anno di pubblicazione2014
FormatoElettronico
Autore/iGrellier J, Ravazzani P, Cardis E
Affiliazioni autoriGrellier J: Centre for Research in Environmental Epidemiology (CREAL), PRBB, Doctor Aiguader, 88, 08003 Barcelona, Spain e CIBER Epidemiología y Salud Pública (CIBERESP), PRBB, Doctor Aiguader, 88, 08003 Barcelona, Spain and Department of Epidemiology and Biostatistics, Imperial College, St. Mary's Campus, Norfolk Place, London W2 1PG, UK Cardis E: Centre for Research in Environmental Epidemiology (CREAL), PRBB, Doctor Aiguader, 88, 08003 Barcelona, Spain e CIBER Epidemiología y Salud Pública (CIBERESP), PRBB, Doctor Aiguader, 88, 08003 Barcelona, Spain Ravazzani P: CNR National Research Council of Italy, Institute of Electronics, Computer and Telecommunication Engineering (IEIIT), Piazza Leonardo da Vinci, 32, 20133 Milan, Italy
Autori CNR e affiliazioni
  • PAOLO GIUSEPPE RAVAZZANI
Lingua/e
  • inglese
AbstractOver the last two decades residential exposure to extremely low frequency magnetic fields (ELF MF) has been associated with childhood leukaemia relatively consistently in epidemiological studies, though causality is still under investigation. We aimed to estimate the cases of childhood leukaemia that might be attributable to exposure to ELF MF in the European Union (EU27), if the associations seen in epidemiological studies were causal. We estimated distributions of ELF MF exposure using studies identified in the existing literature. Individual distributions of exposure were integrated using a probabilistic mixture distribution approach. Exposure-response functions were estimated from the most recently published pooled analysis of epidemiological data. Probabilistic simulation was used to estimate population attributable fractions (AFP) and attributable cases of childhood leukaemia in the EU27. By assigning the literature review-based exposure distribution to all EU27 countries, we estimated the total annual number of cases of leukaemia attributable to ELF MF at between ~ 50 (95% CIs: - 14, 132) and ~ 60 (95% CIs: - 9, 610), depending on whether exposure-response was modelled categorically or continuously, respectively, for a non-threshold effect. This corresponds to between ~ 1.5% and ~ 2.0% of all incident cases of childhood leukaemia occurring annually in the EU27. Considerable uncertainties are due to scarce data on exposure and the choice of exposure-response model, demonstrating the importance of further research into better understanding mechanisms of the potential association between ELF MF exposure and childhood leukaemia and the need for improved monitoring of residential exposures to ELF MF in Europe.
Lingua abstractinglese
Altro abstract-
Lingua altro abstract-
Pagine da55
Pagine a63
Pagine totali-
RivistaEnvironment international
Attiva dal 1978
Editore: Pergamon. - New York
Paese di pubblicazione: Stati Uniti d'America
Lingua: inglese
ISSN: 0160-4120
Titolo chiave: Environment international
Titolo proprio: Environment international.
Titolo abbreviato: Environ. int.
Numero volume della rivista62
Fascicolo della rivista-
DOI10.1016/j.envint.2013.09.017
Verificato da refereeSì: Internazionale
Stato della pubblicazione-
Indicizzazione (in banche dati controllate)
  • Scopus (Codice:2-s2.0-84886305667)
  • ISI Web of Science (WOS) (Codice:000329003000006)
Parole chiaveCancer, Childhood leukaemia, Electromagnetic fields, Low frequency, Magnetic fields, Risk assessment
Link (URL, URI)http://www.sciencedirect.com/science/article/pii/S0160412013002110
Titolo parallelo-
Data di accettazione-
Note/Altre informazioni-
Strutture CNR
  • IEIIT — Istituto di elettronica e di ingegneria dell'informazione e delle telecomunicazioni
Moduli CNR-
Progetti Europei-
Allegati
Grellier et al., 2014 [Env Int] (documento privato )
Tipo documento: application/pdf