Consiglio Nazionale delle Ricerche

Tipo di prodottoArticolo in rivista
TitoloA Numerical Study to Compare Stimulations by Intraoperative Microelectrodes and Chronic Macroelectrodes in the DBS Technique
Anno di pubblicazione2013
FormatoElettronico
Autore/iPaffi A., Apollonio F., Puxeddu M. G., Parazzini M., d'Inzeo G., Ravazzani P., Liberti M.
Affiliazioni autoriPaffi A.: Department of Information Engineering, Electronics and Telecommunication, Sapienza University of Rome, and Italian Inter-University Center for the Study of Electromagnetic Fields and Biological Systems (ICEmB), Genova, Italy Apollonio F.: Department of Information Engineering, Electronics and Telecommunication, Sapienza University of Rome, and Italian Inter-University Center for the Study of Electromagnetic Fields and Biological Systems (ICEmB), Genova, Italy Puxeddu M. G.: Department of Information Engineering, Electronics and Telecommunication, Sapienza University of Rome, Italy Parazzini M.: CNR Consiglio Nazionale delle Ricerche, Istituto di Elettronica e di Ingegneria dell'Informazione e delle Telecomunicazioni IEIIT, Milano, Italy d'Inzeo G.: Department of Information Engineering, Electronics and Telecommunication, Sapienza University of Rome, and Italian Inter-University Center for the Study of Electromagnetic Fields and Biological Systems (ICEmB), Genova, Italy Ravazzani P.: CNR Consiglio Nazionale delle Ricerche, Istituto di Elettronica e di Ingegneria dell'Informazione e delle Telecomunicazioni IEIIT, Milano, Italy Liberti M.: Department of Information Engineering, Electronics and Telecommunication, Sapienza University of Rome, and Italian Inter-University Center for the Study of Electromagnetic Fields and Biological Systems (ICEmB), Genova, Italy
Autori CNR e affiliazioni
  • PAOLO GIUSEPPE RAVAZZANI
  • MARTA PARAZZINI
Lingua/e
  • inglese
AbstractDeep brain stimulation is a clinical technique for the treatment of parkinson's disease based on the electric stimulation, through an implanted electrode, of specific basal ganglia in the brain. To identify the correct target of stimulation and to choose the optimal parameters for the stimulating signal, intraoperative microelectrodes are generally used. However, when they are replaced with the chronic macroelectrode, the effect of the stimulation is often very different. Here, we used numerical simulations to predict the stimulation of neuronal fibers induced by microelectrodes and macroelectrodes placed in different positions with respect to each other. Results indicate that comparable stimulations can be obtained if the chronic macroelectrode is correctly positioned with the same electric center of the intraoperative microelectrode. Otherwise, some groups of fibers may experience a completely different electric stimulation.
Lingua abstractinglese
Altro abstract-
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Pagine da-
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Pagine totali-
RivistaBioMed Research International (Print)
Attiva dal 2012
Editore: Hindawi Publishing Corporation - Cairo
Paese di pubblicazione: Egitto
Lingua: inglese
ISSN: 2314-6133
Titolo chiave: BioMed Research International (Print)
Titolo proprio: BioMed Research International
Titolo abbreviato: BioMed Res. Int.
Numero volume della rivista2013
Fascicolo della rivista-
DOI10.1155/2013/262739
Verificato da refereeSì: Internazionale
Stato della pubblicazione-
Indicizzazione (in banche dati controllate)
  • Scopus (Codice:2-s2.0-84886474984)
  • ISI Web of Science (WOS) (Codice:000325874100001)
Parole chiaveDeep Brain Stimulation, Pulsed Electric Fields, Parkinson Disease, stochastic Resonance Model, Microdosimetry
Link (URL, URI)http://www.hindawi.com/journals/bmri/2013/262739/
Titolo parallelo-
Data di accettazione-
Note/Altre informazioniArticle ID 262739, 7 pages
Strutture CNR
  • IEIIT — Istituto di elettronica e di ingegneria dell'informazione e delle telecomunicazioni
Moduli CNR-
Progetti Europei-
Allegati
Paffi et al., 2013 [BioMed Research International] (documento privato )
Tipo documento: application/pdf