Consiglio Nazionale delle Ricerche

Tipo di prodottoArticolo in rivista
TitoloElectric field and current density distribution in an anatomical head model during transcranial direct current stimulation for tinnitus treatment
Anno di pubblicazione2012
Formato
  • Elettronico
  • Cartaceo
Autore/iParazzini M., Fiocchi S., Ravazzani P.
Affiliazioni autoriParazzini M.: CNR Consiglio Nazionale delle Ricerche, Istituto di Ingegneria Biomedica IEIIT, Milano, Italy Fiocchi S.: CNR Consiglio Nazionale delle Ricerche, Istituto di Ingegneria Biomedica IEIIT, Milano, Italy Ravazzani P.: CNR Consiglio Nazionale delle Ricerche, Istituto di Ingegneria Biomedica IEIIT, Milano, Italy
Autori CNR e affiliazioni
  • MARTA PARAZZINI
  • SERENA FIOCCHI
  • PAOLO GIUSEPPE RAVAZZANI
Lingua/e
  • inglese
AbstractTinnitus is considered an auditory phantom percept. Recently, transcranial direct current stimulation (tDCS) has been proposed as a new approach for tinnitus treatment including, as potential targets of interest, either the temporal and temporoparietal cortex or prefrontal areas. This study investigates and compares the spatial distribution of the magnitude of the electric field and the current density in the brain tissues during tDCS of different brain targets. A numerical method was applied on a realistic human head model to calculate these field distributions in different brain structures, such as the cortex, white matter, cerebellum, hippocampus, medulla oblongata, pons, midbrain, thalamus, and hypothalamus. Moreover, the same distributions were evaluated along the auditory pathways. Results of this study show that tDCS of the left temporoparietal cortex resulted in a widespread diffuse distribution of the magnitude of the electric fields (and also of the current density) on an area of the cortex larger than the target brain region. On the contrary, tDCS of the dorsolateral prefrontal cortex resulted in a stimulation mainly concentrated on the target itself. Differences in the magnitude distribution were also found on the structures along the auditory pathways. A sensitivity analysis was also performed, varying the electrode position and the human head models. Accurate estimation of the field distribution during tDCS in different regions of the head could be valuable to better determine and predict efficacy of tDCS for tinnitus suppression
Lingua abstractinglese
Altro abstract-
Lingua altro abstract-
Pagine da476
Pagine a487
Pagine totali-
RivistaBioelectromagnetics (Online)
Attiva dal 1980
Editore: Wiley-Liss, Inc., - [New York, NY]
Paese di pubblicazione: Stati Uniti d'America
Lingua: inglese
ISSN: 1521-186X
Titolo chiave: Bioelectromagnetics (Online)
Titolo proprio: Bioelectromagnetics (Online)
Titolo abbreviato: Bioelectromagn. (Online)
Titolo alternativo: Bio electro magnetics (Online)
Numero volume della rivista33
Fascicolo della rivista6
DOI10.1002/bem.21708
Verificato da refereeSì: Internazionale
Stato della pubblicazionePublished version
Indicizzazione (in banche dati controllate)
  • Scopus (Codice:s2.0-84864130278)
  • ISI Web of Science (WOS) (Codice:000306669200005)
Parole chiavetranscranial Direct Current Stimulation, Tinnitus, Numerical dosimetry, MRI human head model
Link (URL, URI)http://onlinelibrary.wiley.com/doi/10.1002/bem.21708/full
Titolo parallelo-
Data di accettazione-
Note/Altre informazioni-
Strutture CNR
  • IEIIT — Istituto di elettronica e di ingegneria dell'informazione e delle telecomunicazioni
Moduli CNR
    Progetti Europei-
    Allegati
    • Parazzini et al., 2012 [Bioelectromagnetics]