| Tipo di prodotto | Articolo in rivista |
|---|---|
| Titolo | Electric field and current density distribution in an anatomical head model during transcranial direct current stimulation for tinnitus treatment |
| Anno di pubblicazione | 2012 |
| Formato |
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| Autore/i | Parazzini M., Fiocchi S., Ravazzani P. |
| Affiliazioni autori | Parazzini M.: CNR Consiglio Nazionale delle Ricerche, Istituto di Ingegneria Biomedica IEIIT, Milano, Italy Fiocchi S.: CNR Consiglio Nazionale delle Ricerche, Istituto di Ingegneria Biomedica IEIIT, Milano, Italy Ravazzani P.: CNR Consiglio Nazionale delle Ricerche, Istituto di Ingegneria Biomedica IEIIT, Milano, Italy |
| Autori CNR e affiliazioni |
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| Lingua/e |
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| Abstract | Tinnitus is considered an auditory phantom percept. Recently, transcranial direct current stimulation (tDCS) has been proposed as a new approach for tinnitus treatment including, as potential targets of interest, either the temporal and temporoparietal cortex or prefrontal areas. This study investigates and compares the spatial distribution of the magnitude of the electric field and the current density in the brain tissues during tDCS of different brain targets. A numerical method was applied on a realistic human head model to calculate these field distributions in different brain structures, such as the cortex, white matter, cerebellum, hippocampus, medulla oblongata, pons, midbrain, thalamus, and hypothalamus. Moreover, the same distributions were evaluated along the auditory pathways. Results of this study show that tDCS of the left temporoparietal cortex resulted in a widespread diffuse distribution of the magnitude of the electric fields (and also of the current density) on an area of the cortex larger than the target brain region. On the contrary, tDCS of the dorsolateral prefrontal cortex resulted in a stimulation mainly concentrated on the target itself. Differences in the magnitude distribution were also found on the structures along the auditory pathways. A sensitivity analysis was also performed, varying the electrode position and the human head models. Accurate estimation of the field distribution during tDCS in different regions of the head could be valuable to better determine and predict efficacy of tDCS for tinnitus suppression |
| Lingua abstract | inglese |
| Altro abstract | - |
| Lingua altro abstract | - |
| Pagine da | 476 |
| Pagine a | 487 |
| Pagine totali | - |
| Rivista | Bioelectromagnetics (Online) Attiva dal 1980 Editore: Wiley-Liss, Inc., - [New York, NY] Paese di pubblicazione: Stati Uniti d'America Lingua: inglese ISSN: 1521-186X Titolo chiave: Bioelectromagnetics (Online) Titolo proprio: Bioelectromagnetics (Online) Titolo abbreviato: Bioelectromagn. (Online) Titolo alternativo: Bio electro magnetics (Online) |
| Numero volume della rivista | 33 |
| Fascicolo della rivista | 6 |
| DOI | 10.1002/bem.21708 |
| Verificato da referee | Sì: Internazionale |
| Stato della pubblicazione | Published version |
| Indicizzazione (in banche dati controllate) |
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| Parole chiave | transcranial Direct Current Stimulation, Tinnitus, Numerical dosimetry, MRI human head model |
| Link (URL, URI) | http://onlinelibrary.wiley.com/doi/10.1002/bem.21708/full |
| Titolo parallelo | - |
| Data di accettazione | - |
| Note/Altre informazioni | - |
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| Progetti Europei | - |
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