@prefix prodottidellaricerca: . @prefix istituto: . @prefix prodotto: . istituto:CDS059 prodottidellaricerca:prodotto prodotto:ID5017 . @prefix pubblicazioni: . @prefix unitaDiPersonaleInterno: . unitaDiPersonaleInterno:MATRICOLA1230 pubblicazioni:autoreCNRDi prodotto:ID5017 . @prefix modulo: . modulo:ID2573 prodottidellaricerca:prodotto prodotto:ID5017 . @prefix rdf: . @prefix retescientifica: . prodotto:ID5017 rdf:type retescientifica:ProdottoDellaRicerca , prodotto:TIPO1101 . @prefix rdfs: . prodotto:ID5017 rdfs:label "Early life influences on emotional reactivity: evidence that social enrichment has greater effects than handling on anxiety-like behaviors, neuroendocrine responses to stress and central BDNF levels (Articolo in rivista)"@en . @prefix xsd: . prodotto:ID5017 pubblicazioni:anno "2010-01-01T00:00:00+01:00"^^xsd:gYear . @prefix skos: . prodotto:ID5017 skos:altLabel "
Cirulli F.1), Berry A.1), Bonsignore L.T.1), Capone F.1), D'Andrea I.1), Aloe L.2), Branchi I.1), Alleva E.1) (2010)
Early life influences on emotional reactivity: evidence that social enrichment has greater effects than handling on anxiety-like behaviors, neuroendocrine responses to stress and central BDNF levels
in Neuroscience and biobehavioral reviews
"^^rdf:HTML ; pubblicazioni:autori "Cirulli F.1), Berry A.1), Bonsignore L.T.1), Capone F.1), D'Andrea I.1), Aloe L.2), Branchi I.1), Alleva E.1)"^^xsd:string ; pubblicazioni:paginaInizio "808"^^xsd:string ; pubblicazioni:paginaFine "820"^^xsd:string ; pubblicazioni:numeroVolume "34(6)"^^xsd:string . @prefix ns11: . prodotto:ID5017 pubblicazioni:rivista ns11:ID318270 ; skos:note "ISI Web of Science (WOS)"^^xsd:string ; pubblicazioni:affiliazioni "1) - Section of Behavioural Neuroscience, Department of Cell Biology and Neuroscience, Istituto Superiore di Sanit\u00E0, Viale Regina Elena 299, I-00161, Rome, Italy;\n\n2) - Institute of Neurobiology and Molecular Medicine, CNR, Rome, Italy."^^xsd:string ; pubblicazioni:titolo "Early life influences on emotional reactivity: evidence that social enrichment has greater effects than handling on anxiety-like behaviors, neuroendocrine responses to stress and central BDNF levels"^^xsd:string ; prodottidellaricerca:abstract "During the early post-natal phases the brain is experience-seeking and provided by a considerable plasticity which allows a fine tuning between the external environment and the developing organism. Since the early work of Seymour Levine, an impressive amount of research has clearly shown that stressful experiences exert powerful effects on the brain and body development. These effects can last throughout the entire life span influencing brain function and increasing the risk for depression and anxiety disorders. The mechanisms underlying the effects of early stress on the developing organism have been widely studied in rodents through experimental manipulations of the post-natal environment, such as handling, which have been shown to exert important effects on the emotional phenotype and the response to stress. In the present paper we review the relevant literature and present some original data indicating that, compared to handling, which imposes an external manipulation on the mother\u0096infant relationship, social enrichment, in the form of communal rearing, in mice has very profound effects on animal's emotionality and the response to stress. These effects are also accompanied by important changes in central levels of brain-derived neurotrophic factor. The present data indicate that communal rearing has more pervasive effects than handling, strengthening previous data suggesting that it is a good animal model of reduced susceptibility to depression-like behavior. Overall, the availability of ever more sophisticated animal models represents a fundamental tool to translate basic research data into appropriate interventions for humans raised under traumatic or impoverished situations." ; prodottidellaricerca:prodottoDi modulo:ID2573 , istituto:CDS059 ; pubblicazioni:autoreCNR unitaDiPersonaleInterno:MATRICOLA1230 . @prefix parolechiave: . prodotto:ID5017 parolechiave:insiemeDiParoleChiave . ns11:ID318270 pubblicazioni:rivistaDi prodotto:ID5017 . parolechiave:insiemeDiParoleChiaveDi prodotto:ID5017 .