@prefix prodottidellaricerca: . @prefix istituto: . @prefix prodotto: . istituto:CDS081 prodottidellaricerca:prodotto prodotto:ID305647 . @prefix pubblicazioni: . @prefix unitaDiPersonaleInterno: . unitaDiPersonaleInterno:MATRICOLA950 pubblicazioni:autoreCNRDi prodotto:ID305647 . @prefix rdf: . @prefix retescientifica: . prodotto:ID305647 rdf:type retescientifica:ProdottoDellaRicerca , prodotto:TIPO1101 . @prefix rdfs: . prodotto:ID305647 rdfs:label "Imaging of the dopamine transporter predicts pattern of disease progression and response to levodopa in patients with schizophrenia and parkinsonism: A 2-year follow-up multicenter study (Articolo in rivista)"@en . @prefix xsd: . prodotto:ID305647 pubblicazioni:anno "2014-01-01T00:00:00+01:00"^^xsd:gYear ; pubblicazioni:doi "10.1016/j.schres.2013.11.028"^^xsd:string . @prefix skos: . prodotto:ID305647 skos:altLabel "
Tinazzi, Michele; Morgante, Francesca; Matinella, Angela; Bovi, Tommaso; Cannas, Antonino; Solla, Paolo; Marrosu, Francesco; Nicoletti, Alessandra; Zappia, Mario; Luca, Antonina; Di Stefano, Angela; Morgante, Letterio; Pacchetti, Claudio; Minafra, Brigida; Sciarretta, Massimo; Dallocchio, Carlo; Rossi, Simone; Ulivelli, Monica; Ceravolo, Roberto; Frosini, Daniela; Cipriani, Andrea; Barbui, Corrado (2014)
Imaging of the dopamine transporter predicts pattern of disease progression and response to levodopa in patients with schizophrenia and parkinsonism: A 2-year follow-up multicenter study
in Schizophrenia research (Print)
"^^rdf:HTML ; pubblicazioni:autori "Tinazzi, Michele; Morgante, Francesca; Matinella, Angela; Bovi, Tommaso; Cannas, Antonino; Solla, Paolo; Marrosu, Francesco; Nicoletti, Alessandra; Zappia, Mario; Luca, Antonina; Di Stefano, Angela; Morgante, Letterio; Pacchetti, Claudio; Minafra, Brigida; Sciarretta, Massimo; Dallocchio, Carlo; Rossi, Simone; Ulivelli, Monica; Ceravolo, Roberto; Frosini, Daniela; Cipriani, Andrea; Barbui, Corrado"^^xsd:string ; pubblicazioni:paginaInizio "344"^^xsd:string ; pubblicazioni:paginaFine "349"^^xsd:string ; pubblicazioni:numeroVolume "152"^^xsd:string . @prefix ns10: . prodotto:ID305647 pubblicazioni:rivista ns10:ID496953 ; pubblicazioni:pagineTotali "6"^^xsd:string ; pubblicazioni:numeroFascicolo "2-3"^^xsd:string ; skos:note "ISI Web of Science (WOS)"^^xsd:string ; pubblicazioni:affiliazioni "University of Verona; University of Messina; University of Cagliari; University of Catania; Italian Natl Res Council; University of Messina; IRCCS; Civil Hosp; University of Siena; University of Pisa; University of Verona; University of Verona"^^xsd:string ; pubblicazioni:titolo "Imaging of the dopamine transporter predicts pattern of disease progression and response to levodopa in patients with schizophrenia and parkinsonism: A 2-year follow-up multicenter study"^^xsd:string ; prodottidellaricerca:abstract "Similarly to subjects with degenerative parkinsonism, I-123-FP-CIT SPECT has been reported either normal or abnormal in patients with drug-induced parkinsonism (DIP), challenging the notion that parkinsonism might be entirely due to post-synaptic D2-receptors blockade by antipsychotic drugs. In a previous multicenter cross-sectional study conducted on a large sample of patients with schizophrenia, we identified 97 patients who developed parkinsonism with a similar bi-modal distribution of DAT-SPECT. In this longitudinal study, we reported clinical and imaging features associated with progression of motor disability over 2-year follow-up in 60 out of those 97 patients with schizophrenia and parkinsonism who underwent I-123-FP-CIT SPECT at baseline evaluation (normal SPECT = 33; abnormal SPECT = 27). As second end-point, chronic response to levodopa over a 3-month period was tested in a subgroup of subjects." , "Motor Unified Parkinson's Disease Rating Scale (UPDRS) at follow-up significantly increased in patients with abnormal SPECT. Specifically, a 6-point worsening was demonstrated in 18.5% of the subjects with abnormal SPECT and in none of the subjects with normal SPECT. Levodopa treatment improved motor UPDRS only in the group with abnormal SPECT. After adjustment for possible confounders, linear regression analysis demonstrated that abnormal SPECT findings at baseline were the only predictor of motor disability progression and of better outcome of levodopa treatment." ; prodottidellaricerca:prodottoDi istituto:CDS081 ; pubblicazioni:autoreCNR unitaDiPersonaleInterno:MATRICOLA950 . @prefix parolechiave: . prodotto:ID305647 parolechiave:insiemeDiParoleChiave . ns10:ID496953 pubblicazioni:rivistaDi prodotto:ID305647 . parolechiave:insiemeDiParoleChiaveDi prodotto:ID305647 .