@prefix prodottidellaricerca: . @prefix istituto: . @prefix prodotto: . istituto:CDS040 prodottidellaricerca:prodotto prodotto:ID27595 . @prefix modulo: . modulo:ID5952 prodottidellaricerca:prodotto prodotto:ID27595 . @prefix pubblicazioni: . @prefix unitaDiPersonaleEsterno: . unitaDiPersonaleEsterno:ID14805 pubblicazioni:autoreCNRDi prodotto:ID27595 . @prefix rdf: . prodotto:ID27595 rdf:type prodotto:TIPO1101 . @prefix retescientifica: . prodotto:ID27595 rdf:type retescientifica:ProdottoDellaRicerca . @prefix rdfs: . prodotto:ID27595 rdfs:label "Host-derived loss of dentin matrix stiffness associated with solubilization of collagen. (Articolo in rivista)"@en . @prefix xsd: . prodotto:ID27595 pubblicazioni:anno "2009-01-01T00:00:00+01:00"^^xsd:gYear . @prefix skos: . prodotto:ID27595 skos:altLabel "
Carrilho MR, Tay FR, Donnelly AM, Agee KA, Tj\u00E4derhane L, Mazzoni A, Breschi L, Foulger S, Pashley DH. (2009)
Host-derived loss of dentin matrix stiffness associated with solubilization of collagen.
"^^rdf:HTML ; pubblicazioni:autori "Carrilho MR, Tay FR, Donnelly AM, Agee KA, Tj\u00E4derhane L, Mazzoni A, Breschi L, Foulger S, Pashley DH."^^xsd:string ; pubblicazioni:paginaInizio "373"^^xsd:string ; pubblicazioni:paginaFine "380"^^xsd:string ; pubblicazioni:numeroVolume "90"^^xsd:string ; skos:note "ISI Web of Science (WOS)"^^xsd:string ; pubblicazioni:affiliazioni "Department of Oral Biology, School of Dentistry, Medical College of Georgia, Augusta, Georgia; Department of Restorative Dentistry, Piracicaba School of Dentistry, University of Campinas, Piracicaba/SP, Brazil; Department of Endodontics, School of Dentistry, Medical College of Georgia, Augusta, Georgia Institute of Dentistry, University of Oulu and Oulu University Hospital, Oulu, Finland; Department of SAU and FAL, University of Bologna, Bologna, Italy; Division of Dental Sciences and Biomaterials, Department of Biomedicine, University of Trieste, Trieste, Italy; IGM-CNR, Unit of Bologna c/o IOR, Bologna, Italy; Department of Material Sciences Engineering, Clemson University, Clemson, South Carolina"^^xsd:string ; pubblicazioni:titolo "Host-derived loss of dentin matrix stiffness associated with solubilization of collagen."^^xsd:string ; prodottidellaricerca:abstract "Matrix metalloproteinases (MMPs) bound to dentin matrices are activated during adhesive bonding procedures and are thought to contribute to the progressive degradation of resin-dentin bonds over time. The purpose of this study was to evaluate the changes in mechanical, biochemical, and structural properties of demineralized dentin treated with or without chlorhexidine (CHX), a known MMP-inhibitor. After demineralizing dentin beams in EDTA or phosphoric acid (PA), the baseline modulus of elasticity (E) of each beam was measured by three-point flexure. Specimens were pretreated with water (control) or with 2% CHX (experimental) and then incubated in artificial saliva (AS) at 37 degrees C for 4 weeks. The E of each specimen was remeasured weekly and, the media was analyzed for solubilized dentin collagen at first and fourth week of incubation. Some specimens were processed for electron microscopy (TEM) immediately after demineralization and after 4 weeks of incubation. In EDTA and PA-demineralized specimens, the E of the control specimens fell (p < 0.05) after incubation in AS, whereas there were no changes in E of the CHX-pretreated specimens over time. More collagen was solubilized from PA-demineralized controls (p < 0.05) than from EDTA-demineralized matrices after 1 or 4 weeks. Less collagen (p < 0.05) was solubilized from CHX-pretreated specimens demineralized in EDTA compared with PA. TEM examination of control beams revealed that prolonged demineralization of dentin in 10% PA (12 h) did not denature the collagen fibrils." ; prodottidellaricerca:prodottoDi modulo:ID5952 , istituto:CDS040 ; pubblicazioni:autoreCNR unitaDiPersonaleEsterno:ID14805 . @prefix parolechiave: . prodotto:ID27595 parolechiave:insiemeDiParoleChiave . parolechiave:insiemeDiParoleChiaveDi prodotto:ID27595 .