@prefix pubblicazioni: . @prefix unitaDiPersonaleInterno: . @prefix prodotto: . unitaDiPersonaleInterno:MATRICOLA42109 pubblicazioni:autoreCNRDi prodotto:ID24194 . unitaDiPersonaleInterno:MATRICOLA5478 pubblicazioni:autoreCNRDi prodotto:ID24194 . @prefix prodottidellaricerca: . @prefix istituto: . istituto:CDS035 prodottidellaricerca:prodotto prodotto:ID24194 . @prefix modulo: . modulo:ID6306 prodottidellaricerca:prodotto prodotto:ID24194 . @prefix rdf: . @prefix retescientifica: . prodotto:ID24194 rdf:type retescientifica:ProdottoDellaRicerca , prodotto:TIPO1101 . @prefix rdfs: . prodotto:ID24194 rdfs:label "Diffuse, marked, reversible impairment in coronary microcirculation in stress cardiomyopathy: A Doppler transthoracic echo study (Articolo in rivista)"@en . @prefix xsd: . prodotto:ID24194 pubblicazioni:anno "2009-01-01T00:00:00+01:00"^^xsd:gYear ; pubblicazioni:doi "10.1080/07853890903022793"^^xsd:string . @prefix skos: . prodotto:ID24194 skos:altLabel "
Rigo F, Sicari R, Citro R, Ossena G, Buja P, Picano E. (2009)
Diffuse, marked, reversible impairment in coronary microcirculation in stress cardiomyopathy: A Doppler transthoracic echo study
in Annals of medicine (Helsinki)
"^^rdf:HTML ; pubblicazioni:autori "Rigo F, Sicari R, Citro R, Ossena G, Buja P, Picano E."^^xsd:string ; pubblicazioni:paginaInizio "1"^^xsd:string ; pubblicazioni:paginaFine "9"^^xsd:string ; pubblicazioni:numeroVolume "2"^^xsd:string . @prefix ns11: . prodotto:ID24194 pubblicazioni:rivista ns11:ID505028 ; skos:note "ubMe"^^xsd:string ; pubblicazioni:affiliazioni "Istituto di Fisiologia Clinica del CNR"^^xsd:string ; pubblicazioni:titolo "Diffuse, marked, reversible impairment in coronary microcirculation in stress cardiomyopathy: A Doppler transthoracic echo study"^^xsd:string ; prodottidellaricerca:abstract "Abstract\nThe aim of the study was to assess coronary flow reserve (CFR) in tako-tsubo cardiomyopathy (TC). METHODS AND RESULTS: Thirty consecutive patients (5 males; age 68+/-12 years) meeting diagnostic criteria for TC were evaluated with transthoracic dipyridamole (0.84 mg/kg over 6 min) stress echo and pulsed Doppler CFR assessment on mid-distal left anterior descending (LAD) and posterior descending of right coronary artery (PD). Wall motion score index (WMSI) was evaluated at base-line and during stress. All patients were followed up clinically and-on day 1, day 7 (+/-2 days), and at 6 months-by repeat stress echo. Thirty gender- matched controls were also studied. CFR was obtained in all patients on LAD and in 25 on PD. All showed a transient apical ballooning in the acute phase (day 1 of admission), with progressive recovery of function at follow-up (WMSI, day 1 = 1.7+/-0.2; day 7 = 1.4+/-0.14; 6 months = 1.0+/-0.1; P<0.001 versus day 1 and versus day 7). When compared to controls (3.1+/-0.5), CFR on LAD was reduced on day 1 (1.8+/-0.24, P<0.001) (upon admission), and it showed early recovery in the subacute (pre-discharge) assessment on day 7. CFR values remained stable at 6-month follow-up (2.6+/-0.3). CONCLUSION: TC is characterized by a profound, diffuse coronary microcirculatory disturbance in the acute phase, with early reversal to near-normal values within a few days, paralleling the functional recovery in regional wall motion."@en ; prodottidellaricerca:prodottoDi istituto:CDS035 , modulo:ID6306 ; pubblicazioni:autoreCNR unitaDiPersonaleInterno:MATRICOLA42109 , unitaDiPersonaleInterno:MATRICOLA5478 . ns11:ID505028 pubblicazioni:rivistaDi prodotto:ID24194 .