@prefix pubblicazioni: . @prefix unitaDiPersonaleInterno: . @prefix prodotto: . unitaDiPersonaleInterno:MATRICOLA28002 pubblicazioni:autoreCNRDi prodotto:ID201065 . @prefix prodottidellaricerca: . @prefix istituto: . istituto:CDS035 prodottidellaricerca:prodotto prodotto:ID201065 . @prefix modulo: . modulo:ID7359 prodottidellaricerca:prodotto prodotto:ID201065 . @prefix rdf: . @prefix retescientifica: . prodotto:ID201065 rdf:type retescientifica:ProdottoDellaRicerca , prodotto:TIPO1101 . @prefix rdfs: . prodotto:ID201065 rdfs:label "Paper 4: EUROCAT Statistical Monitoring: Identification and Investigation of Ten Year Trends of Congenital Anomalies in Europe (Articolo in rivista)"@en . @prefix xsd: . prodotto:ID201065 pubblicazioni:anno "2011-01-01T00:00:00+01:00"^^xsd:gYear ; pubblicazioni:doi "10.1002/bdra.20778"^^xsd:string . @prefix skos: . prodotto:ID201065 skos:altLabel "
Bianchi, Fabrizio (1); Kelly, Alan (4); Nelen, Vera (2); Calzolari, Elisa (2); Barisic, Ingeborg (2); Garne, Ester (2); Tucker, David (2); Bakker, Marian (2); Dolk, Helen (3); Wellesley, Diana (2); Boyd, Patricia (2); Khoshnood, Babak (2); Rankin, Judith; Verellen-Dumoulin, Christine (2); Mc Donnel, Bob (2); Mullaney, Carmel (2); Greenlees, Ruth (3); Loane, Marie (3); Densem, James (5); Rissmann, Anke (2); Addor, Marie-Calude (2); Drapper, Elizabeth (2); Thames, Valley (2) (2011)
Paper 4: EUROCAT Statistical Monitoring: Identification and Investigation of Ten Year Trends of Congenital Anomalies in Europe
in Birth defects research. Part A. Clinical and molecular teratology (Online)
"^^rdf:HTML ; pubblicazioni:autori "Bianchi, Fabrizio (1); Kelly, Alan (4); Nelen, Vera (2); Calzolari, Elisa (2); Barisic, Ingeborg (2); Garne, Ester (2); Tucker, David (2); Bakker, Marian (2); Dolk, Helen (3); Wellesley, Diana (2); Boyd, Patricia (2); Khoshnood, Babak (2); Rankin, Judith; Verellen-Dumoulin, Christine (2); Mc Donnel, Bob (2); Mullaney, Carmel (2); Greenlees, Ruth (3); Loane, Marie (3); Densem, James (5); Rissmann, Anke (2); Addor, Marie-Calude (2); Drapper, Elizabeth (2); Thames, Valley (2)"^^xsd:string ; pubblicazioni:paginaInizio "31"^^xsd:string ; pubblicazioni:paginaFine "43"^^xsd:string ; pubblicazioni:numeroVolume "91"^^xsd:string . @prefix ns11: . prodotto:ID201065 pubblicazioni:rivista ns11:ID75776 ; pubblicazioni:pagineTotali "13"^^xsd:string ; pubblicazioni:numeroFascicolo "1"^^xsd:string ; skos:note "ISI Web of Science (WOS)"^^xsd:string ; pubblicazioni:affiliazioni "(1) CNR-IFC, Pisa; (2) EUROCAT Working Group; (3) EUROCAT Central Registry Belfast; (4) Department of Public Health & Primary Care, Trinity College Dublin; (5) BioMedical Computing Limited, Innovation Centre, East Sussex"^^xsd:string ; pubblicazioni:titolo "Paper 4: EUROCAT Statistical Monitoring: Identification and Investigation of Ten Year Trends of Congenital Anomalies in Europe"^^xsd:string ; prodottidellaricerca:abstract "BACKGROUND: As part of EUROCAT's surveillance of congenital anomalies in Europe, a statistical monitoring system has been developed to detect recent clusters or long-term (10 year) time trends. The purpose of this article is to describe the system for the identification and investigation of 10-year time trends, conceived as a \\\"screening'' tool ultimately leading to the identification of trends which may be due to changing teratogenic factors. METHODS: The EUROCAT database consists of all cases of congenital anomalies including livebirths, fetal deaths from 20 weeks gestational age, and terminations of pregnancy for fetal anomaly. Monitoring of 10-year trends is performed for each registry for each of 96 non-independent EUROCAT congenital anomaly subgroups, while Pan-Europe analysis combines data from all registries. The monitoring results are reviewed, prioritized according to a prioritization strategy, and communicated to registries for investigation. Twenty-one registries covering over 4 million births, from 1999 to 2008, were included in monitoring in 2010. CONCLUSIONS: Significant increasing trends were detected for abdominal wall anomalies, gastroschisis, hypospadias, Trisomy 18 and renal dysplasia in the Pan-Europe analysis while 68 increasing trends were identified in individual registries. A decreasing trend was detected in over one-third of anomaly subgroups in the Pan-Europe analysis, and 16.9% of individual registry tests. Registry preliminary investigations indicated that many trends are due to changes in data quality, ascertainment, screening, or diagnostic methods. Some trends are inevitably chance phenomena related to multiple testing, while others seem to represent real and continuing change needing further investigation and response by regional/national public health authorities"@en ; prodottidellaricerca:prodottoDi istituto:CDS035 , modulo:ID7359 ; pubblicazioni:autoreCNR unitaDiPersonaleInterno:MATRICOLA28002 . ns11:ID75776 pubblicazioni:rivistaDi prodotto:ID201065 .