@prefix pubblicazioni: . @prefix unitaDiPersonaleEsterno: . @prefix prodotto: . unitaDiPersonaleEsterno:ID28 pubblicazioni:autoreCNRDi prodotto:ID188144 . @prefix prodottidellaricerca: . @prefix istituto: . istituto:CDS009 prodottidellaricerca:prodotto prodotto:ID188144 . unitaDiPersonaleEsterno:ID4644 pubblicazioni:autoreCNRDi prodotto:ID188144 . unitaDiPersonaleEsterno:ID6007 pubblicazioni:autoreCNRDi prodotto:ID188144 . @prefix unitaDiPersonaleInterno: . unitaDiPersonaleInterno:MATRICOLA7391 pubblicazioni:autoreCNRDi prodotto:ID188144 . @prefix modulo: . modulo:ID7740 prodottidellaricerca:prodotto prodotto:ID188144 . @prefix rdf: . @prefix retescientifica: . prodotto:ID188144 rdf:type retescientifica:ProdottoDellaRicerca , prodotto:TIPO1101 . @prefix rdfs: . prodotto:ID188144 rdfs:label "Respiratory gated PET/CT in a European multicentre retrospective study: added diagnostic value in detection and characterization of lung lesions (Articolo in rivista)"@en . @prefix xsd: . prodotto:ID188144 pubblicazioni:anno "2012-01-01T00:00:00+01:00"^^xsd:gYear ; pubblicazioni:doi "10.1007/s00259-012-2148-2"^^xsd:string . @prefix skos: . prodotto:ID188144 skos:altLabel "
Luca Guerra; Elena De Ponti; Federica Elisei; Valentino Bettinardi; Claudio Landoni; Maria Picchio; Maria Carla Gilardi; Annibale Versari; Federica Fioroni; Miroslaw Dziuk; Magdalena Koza; Ren\u00E9e Ahond-Vionnet; Bertrand Collin; Cristina Messa. (2012)
Respiratory gated PET/CT in a European multicentre retrospective study: added diagnostic value in detection and characterization of lung lesions
in European journal of nuclear medicine and molecular imaging (Print)
"^^rdf:HTML ; pubblicazioni:autori "Luca Guerra; Elena De Ponti; Federica Elisei; Valentino Bettinardi; Claudio Landoni; Maria Picchio; Maria Carla Gilardi; Annibale Versari; Federica Fioroni; Miroslaw Dziuk; Magdalena Koza; Ren\u00E9e Ahond-Vionnet; Bertrand Collin; Cristina Messa."^^xsd:string ; pubblicazioni:paginaInizio "1381"^^xsd:string ; pubblicazioni:paginaFine "1390"^^xsd:string ; pubblicazioni:url "http://www.springerlink.com/content/p5p4q58204700432/"^^xsd:string ; pubblicazioni:numeroVolume "39"^^xsd:string . @prefix ns12: . prodotto:ID188144 pubblicazioni:rivista ns12:ID69266 ; pubblicazioni:numeroFascicolo "9"^^xsd:string ; skos:note "PubMe"^^xsd:string , "ISI Web of Science (WOS)"^^xsd:string ; pubblicazioni:affiliazioni "Nuclear Medicine, San Gerardo Hospital, Monza, Italy. Medical Physics, San Gerardo Hospital, Monza, Italy. Nuclear Medicine, San Raffaele Scientific Institute, Milan, Italy. Institute for Bioimaging and Molecular Physiology, National Research Council, Ssgrate (MI), Italy. University of Milano-Bicocca, Milan, Italy. Tecnomed Foundation, University of Milano-Bicocca, Milan, Italy. Nuclear Medicine, Scientific Institute\nSanta Maria Nuova Hospital, Reggio Emilia, Italy. Medical Physics, Scientific Institute Santa Maria Nuova Hospital, Reggio Emilia, Italy. Department of Nuclear Medicine, Military Institute of Medicine, Masovian PET-CT Centre, Warsaw, Poland. Masovian PET-CT Centre, Euromedic Diagnostic, Warsaw, Poland. Service de M\u00E9decine Nucl\u00E9aire, H\u00F4pital Pierre Beregovoy, Nevers Cedex, France"^^xsd:string ; pubblicazioni:titolo "Respiratory gated PET/CT in a European multicentre retrospective study: added diagnostic value in detection and characterization of lung lesions"^^xsd:string ; prodottidellaricerca:abstract "PURPOSE: The aim of our work is to evaluate the added diagnostic value of respiratory gated (4-D) positron emission tomography/computed tomography (PET/CT) in lung lesion detection/characterization in a large patient population of a multicentre retrospective study.\nMETHODS: The data of 155 patients (89 men, 66 women, mean age 63.9 \u00B1 11.1 years) from 5 European centres and submitted to standard (3-D) and 4-D PET/CT were retrospectively analysed. Overall, 206 lung lesions were considered for the analysis (mean \u00B1 SD lesions dimension 14.7 \u00B1 11.8 mm). Maximum standardized uptake values (SUV(max)) and lesion detectability were assessed for both 3-D and 4-D PET/CT studies; 3-D and 4-D PET/CT findings were compared to clinical follow-up as standard reference.\nRESULTS: Mean \u00B1 SD 3-D and 4-D SUV(max) values were 5.2 \u00B1 5.1 and 6.8 \u00B1 6.1 (p < 0.0001), respectively, with an average percentage increase of 30.8 %. In 3-D PET/CT, 86 of 206 (41.7 %) lesions were considered positive, 70 of 206 (34 %) negative and 50 of 206 (24.3 %) equivocal, while in 4-D PET/CT 117 of 206 (56.8 %) lesions were defined as positive, 80 of 206 (38.8 %) negative and 9 of 206 (4.4 %) equivocal. In 34 of 50 (68 %) 3-D equivocal lesions follow-up data were available and the presence of malignancy was confirmed in 21 of 34 (61.8 %) lesions, while in 13 of 34 (38.2 %) was excluded. In 31 of these 34 controlled lesions, 20 of 34 (58.8 %) and 11 of 34 (32.4 %) were correctly classified by 4-D PET/CT as positive and negative, respectively; 3 of 34 (8.8 %) remained equivocal. With equivocal lesions classified as positive, the overall accuracy of 3-D and 4-D was 85.7 and 92.8 %, respectively, while the same figures were 80.5 and 94.2 % when equivocal lesions were classified as negative.\nCONCLUSION: The respiratory gated PET/CT technique is a valuable clinical tool in diagnosing lung lesions, improving quantification and confidence in reporting, reducing 3-D undetermined findings and increasing the overall accuracy in lung lesion detection and characterization."@en ; prodottidellaricerca:prodottoDi modulo:ID7740 , istituto:CDS009 ; pubblicazioni:autoreCNR unitaDiPersonaleEsterno:ID28 , unitaDiPersonaleInterno:MATRICOLA7391 , unitaDiPersonaleEsterno:ID6007 , unitaDiPersonaleEsterno:ID4644 . @prefix parolechiave: . prodotto:ID188144 parolechiave:insiemeDiParoleChiave . ns12:ID69266 pubblicazioni:rivistaDi prodotto:ID188144 . parolechiave:insiemeDiParoleChiaveDi prodotto:ID188144 .