@prefix pubblicazioni: . @prefix unitaDiPersonaleInterno: . @prefix prodotto: . unitaDiPersonaleInterno:MATRICOLA42109 pubblicazioni:autoreCNRDi prodotto:ID109079 . @prefix prodottidellaricerca: . @prefix istituto: . istituto:CDS035 prodottidellaricerca:prodotto prodotto:ID109079 . @prefix modulo: . modulo:ID6306 prodottidellaricerca:prodotto prodotto:ID109079 . @prefix rdf: . @prefix retescientifica: . prodotto:ID109079 rdf:type retescientifica:ProdottoDellaRicerca , prodotto:TIPO1105 . @prefix rdfs: . prodotto:ID109079 rdfs:label "Force-frequency relationship during dobutamine stress echocardiography predicts exercise tolerance and BNP levels in patients with chronic congestive heart failure (Abstract in rivista)"@en . @prefix xsd: . prodotto:ID109079 pubblicazioni:anno "2007-01-01T00:00:00+01:00"^^xsd:gYear . @prefix skos: . prodotto:ID109079 skos:altLabel "
Ciampi Q.; Della Porta M.; Bombardini T.; Petruzziello B.; Caputo S.; Manganiello V.; Picano E.; Villari B. (2007)
Force-frequency relationship during dobutamine stress echocardiography predicts exercise tolerance and BNP levels in patients with chronic congestive heart failure
in European Journal of Echocardiography, 2007
"^^rdf:HTML ; pubblicazioni:autori "Ciampi Q.; Della Porta M.; Bombardini T.; Petruzziello B.; Caputo S.; Manganiello V.; Picano E.; Villari B."^^xsd:string ; pubblicazioni:convegno "European Journal of Echocardiography"^^xsd:string ; pubblicazioni:note "In: European Journal of Echocardiography, vol. December Suppl Oxford Journals, 2007."^^xsd:string ; pubblicazioni:descrizioneSinteticaDelProdotto "Purpose: D obutamine stress echocardiography (DSE) is widely used to evaluate myocardial contractile reserve; it provides prognostic information in patients with chronic congestive heart failure (CHF). The force?frequency relationship (FFR) is a method for evaluate LV contractility during DSE . The aim of our study is to assess the relationship among FFR, BNP levels, and aerobic exercise capacity in CHF patients. Methods and materials: 37 CHF patients (age 67\u00B18 years, 54% with an ischemic etiology), underwent high dose DSE (up to 40 m g/kg/min). FFR was determined as a ratio between systolic cuff pressure and end-systolic volume (biplane using a Simposon rule) assessed at baseline and peak DSE . BNP levels were determined on blood samples withdrawn at baseline. After a few hours, CHF patients underwent cardiopulmonary exercise test with expired gas measurement. Results: Mean ejection fraction was 32\u00B17% and NHYA class 2.5\u00B10.6. FFR was directly related to peak oxygen consumption (Figure Left), LV ejection fraction (r=0.398, p=0.015) and mitral annulus peak systolic velocity (r=0.428, p=0.013). FFR was inversely related to NYHA class (r=-0.43, p=0.013), LV end-diastolic diameter (r=-0.377, p=0.022), LV intraventricular dyssynchrony (r=-0.394, p=0.016), and BNP levels (Figure Right). At multiple regression analysis, FFR (B=0.502, p= 0.004) and E/Ea ratio (B=-0.336, p=0.044) were the best predictors of exercise tolerance. Conclusions: In patients with stable CHF, impaired myocardial contractility during DSE is related to higher BNP levels and poorer exercise tolerance."^^xsd:string ; pubblicazioni:titolo "Force-frequency relationship during dobutamine stress echocardiography predicts exercise tolerance and BNP levels in patients with chronic congestive heart failure"^^xsd:string ; prodottidellaricerca:prodottoDi istituto:CDS035 , modulo:ID6306 ; pubblicazioni:autoreCNR unitaDiPersonaleInterno:MATRICOLA42109 . @prefix parolechiave: . prodotto:ID109079 parolechiave:insiemeDiParoleChiave . parolechiave:insiemeDiParoleChiaveDi prodotto:ID109079 .