@prefix prodottidellaricerca: . @prefix istituto: . @prefix prodotto: . istituto:CDS009 prodottidellaricerca:prodotto prodotto:ID10559 . @prefix pubblicazioni: . @prefix unitaDiPersonaleEsterno: . unitaDiPersonaleEsterno:ID9872 pubblicazioni:autoreCNRDi prodotto:ID10559 . @prefix modulo: . modulo:ID2644 prodottidellaricerca:prodotto prodotto:ID10559 . @prefix rdf: . @prefix retescientifica: . prodotto:ID10559 rdf:type retescientifica:ProdottoDellaRicerca , prodotto:TIPO1101 . @prefix rdfs: . prodotto:ID10559 rdfs:label "Outcome measures and rehabilitation treatment in patients affected by Charcot-Marie-Tooth neuropathy: a pilot study. (Articolo in rivista)"@en . @prefix xsd: . prodotto:ID10559 pubblicazioni:anno "2011-01-01T00:00:00+01:00"^^xsd:gYear . @prefix skos: . prodotto:ID10559 skos:altLabel "
Maggi G. 1, Monti Bragadin M. 2,3, Padua L. 3,4, Fiorina E. 2, Bellone E. 2, Grandis M. 2, Reni L. 2, Bennicelli A. 2, Grosso M. 2, Saporiti R. 5, Scorsone D. 5, Zuccarino R. 2, Crimi E. 5, Schenone A. 2,6 (2011)
Outcome measures and rehabilitation treatment in patients affected by Charcot-Marie-Tooth neuropathy: a pilot study.
in American journal of physical medicine & rehabilitation
"^^rdf:HTML ; pubblicazioni:autori "Maggi G. 1, Monti Bragadin M. 2,3, Padua L. 3,4, Fiorina E. 2, Bellone E. 2, Grandis M. 2, Reni L. 2, Bennicelli A. 2, Grosso M. 2, Saporiti R. 5, Scorsone D. 5, Zuccarino R. 2, Crimi E. 5, Schenone A. 2,6"^^xsd:string ; pubblicazioni:paginaInizio "628"^^xsd:string ; pubblicazioni:paginaFine "637"^^xsd:string ; pubblicazioni:numeroVolume "90"^^xsd:string . @prefix ns11: . prodotto:ID10559 pubblicazioni:rivista ns11:ID495632 ; skos:note "ISI Web of Science (WOS)"^^xsd:string ; pubblicazioni:affiliazioni "1. Department of Rehabilitation Medicine, San Martino Hospital, Genoa.\n2. Department of Neurosciences, Ophthalmology and Genetics, University of Genoa.\n3. Don Gnocchi Foundation, Milan.\n4. Department of Neurosciences, UCSC University, Rome.\n5. Department of Internal Medicine and Medical Specializations, University of Genoa.\n6. CNR Institute of Bioimages and Molecular Physiology, Genoa.\n"^^xsd:string ; pubblicazioni:titolo "Outcome measures and rehabilitation treatment in patients affected by Charcot-Marie-Tooth neuropathy: a pilot study."^^xsd:string ; prodottidellaricerca:abstract "OBJECTIVE: : We evaluated the sensitivity of various rehabilitation and lung function scales to detect differences between people with Charcot-Marie-Tooth (CMT) disease and healthy controls. We also studied whether these measurements are sensitive to disclose changes in patients with CMT disease after rehabilitative treatment.\n\nDESIGN: : Eight patients with different types of CMT participated in the study. Data were gathered at baseline; at the end of the treadmill training, stretching, respiratory, and proprioceptive exercise (TreSPE) treatment period; and after a washout period of 6 mos. The following instruments were used for data collection: Medical Research Council scale for lower limb strength; Tinetti Balance Scale; Physical Performance Battery; ankle angle, oxygen consumption, and lung function tests; peak treadmill velocity and slope; time to walk 6 m; and CMT Neuropathy Score. The participants underwent TreSPE treatment twice every week for 8 wks.\n\nRESULTS: : All rehabilitative measures were significantly worse in subjects with CMT disease than in healthy controls. Lung function was always normal except for the maximum expiratory pressure and maximum inspiratory pressure. No dropouts or worsening in any of the different outcome measures were observed after TreSPE. The ankle angle and the time to walk 6 m were the only measures that significantly improved after treatment.\n\nCONCLUSIONS: : The rehabilitative outcome measures used in this protocol are useful in detecting clinical impairment in people with CMT disease. Lung function tests were confirmed to be minimally abnormal in patients with CMT disease. The TreSPE treatment, besides being safe and well tolerated, induced some training effects in CMT neuropathy, in the absence of lung function amelioration and effort tolerance. Follow-up showed that CMT patients should be treated at least twice every year because a regression of all outcome measures to the baseline state was found after a 6-mo washout period." ; prodottidellaricerca:prodottoDi modulo:ID2644 , istituto:CDS009 ; pubblicazioni:autoreCNR unitaDiPersonaleEsterno:ID9872 . @prefix parolechiave: . prodotto:ID10559 parolechiave:insiemeDiParoleChiave . ns11:ID495632 pubblicazioni:rivistaDi prodotto:ID10559 . parolechiave:insiemeDiParoleChiaveDi prodotto:ID10559 .