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Istituto per lo studio dei materiali nanostrutturati

Torna all'elenco Brevetti anno 2016

Brevetti e altre tipologie di proprietÓ industriali

Tipo: Brevetto di invenzione industriale

Titolo: Formulations used to treat ocular diseases comprising e.g. macular edema, uveitis, comprise active ingredients incorporated in nanostructured systems

Anno di pubblicazione: 2016

Tipo di brevetto: Internazionale

Numero: WO2016055976-A1

Nazione/i di deposito: ITALIA

Autori: BLANCO AR, BONDI' ML, CAVALLARO G, CONSOLI MGL, CRAPARO EF, CUZZOCREA S, DEIDDA I, ESPOSITO E, GIAMMONA G, GRANATA G, GUARNERI P, LA MARCA C, LICCIARDI M, PASERGI S, PITARRESI G, SALADINO P, VIOLA S

Affiliazioni autori: ISMN-CNR, STEBICEF UNIPA,

Autori CNR:

  • MARIA LUISA BONDI'
  • PATRIZIA GUARNERI

Lingua: inglese

Descrizione: Abstract: NOVELTY - Formulations comprise an active ingredient comprising silibinin, sorafenib, curcumin, or latanoprost. The active ingredient is incorporated in lipid nanoparticle systems of SLN (solid lipid nanoparticles), and NLC (nanostructured lipid carriers) type, calixarene-based nanostructured systems, micellar and nanoparticle systems based on amphiphilic inulin copolymers, possibly in the presence of mucoadhesives. USE - The formulations are useful for topical treatment of ocular diseases, where the ocular diseases are neurodegenerative ocular diseases, and the neurodegenerative ocular disease comprises choroidal neovascularization, age-related macular degeneration, macular edema, neovascular glaucoma, retinopathy of prematurity, diabetic retinopathy, uveitis, endophthalmitis, retinitis, choroiditis, chorioretinitis, or retinal complications of systemic diseases (all claimed). Test details are described but no results given.

Istituto richiedente: ISMN

Parole chiave:

  • Formulations
  • silibinin
  • sorafenib
  • curcumin
  • or latanoprost
  • solid lipid nanoparticles (SLN)
  • nanostructured lipid carriers (NLC)
  • micellar and nanoparticle systems
  • mucoadhesives.

Strutture CNR:

Moduli:

 
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