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Istituto di scienze e tecnologie della cognizione

Torna all'elenco Contributi in rivista anno 2014

Contributo in rivista

Tipo: Articolo in rivista

Titolo: Role of PET and SPECT in the study of amyotrophic lateral sclerosis.

Anno di pubblicazione: 2014

Formato: Elettronico

Autori: Cistaro, Angelina; Cuccurullo, Vincenzo; Quartuccio, Natale; Pagani, Marco; Valentini, Maria Consuelo; Mansi, Luigi

Affiliazioni autori: Positron Emission Tomography Centre IRMET S.p.A., Euromedic Inc., V. O. Vigliani 89/A, 10136 Turin, Italy PET Pediatric AIMNInterGroup, V. O. Vigliani 89/A, 10136 Turin, Italy Institute of Cognitive Sciences and Technologies, National Research Council, Piazzale Aldo Moro 7, 00185 Rome, Italy NuclearMedicineUnit,Department ofClinical and Experimental Internistic "F.Magrassi, A. Lanzara", SecondaUniversit`a di Napoli, Vico Luigi de Crecchio 16, 80138 Naples, Italy Nuclear Medicine Unit, Department of Biomedical Sciences and of Morphological and Functional Images, University of Messina, Via Consolare Valeria 1, 98125Messina, Italy Department of Nuclear Medicine, Karolinska University Hospital, Solnav¨agen 1, Solna, 171 77 Stockholm, Sweden Department of Neuroradiology, San Giovanni Battista-OIRM-S.Anna-CTO Hospital, Via Cherasco 15, 10126 Turin, Italy

Autori CNR:


Lingua: inglese

Abstract: Amyotrophic lateral sclerosis has been defined as a "heterogeneous group of neurodegenerative syndromes characterized by progressive muscle paralysis caused by the degeneration of motor neurons allocated in primary motor cortex, brainstem, and spinal cord." A comprehensive diagnostic workup for ALS usually includes several electrodiagnostic, clinical laboratory and genetic tests. Neuroimaging exams, such as computed tomography, magnetic resonance imaging and spinal cord myelogram, may also be required. Nuclear medicine, with PET and SPECT, may also play a role in the evaluation of patients with ALS, and provide additional information to the clinicians. This paper aims to offer to the reader a comprehensive review of the different radiotracers for the assessment of the metabolism of glucose (FDG), the measurement of cerebral blood flow (CBF), or the evaluation of neurotransmitters, astrocytes, and microglia by means of newer and not yet clinically diffuse radiopharmaceuticals.

Lingua abstract: inglese

Pagine totali: 7


BioMed Research International Hindawi Publishing Corporation
Paese di pubblicazione: Egitto
Lingua: inglese
ISSN: 2314-6141

Numero volume: 2014

DOI: 10.1155/2014/237437

Referee: Sė: Internazionale

Indicizzato da: ISI Web of Science (WOS) [24818133]

Parole chiave:

  • PET
  • amyotrophic lateral sclerosis

Strutture CNR:


Allegati: 2014 BMRI SPECT & PET in ALS (application/pdf)

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