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Istituto di scienze e tecnologie della cognizione

Torna all'elenco Contributi in rivista anno 2014

Contributo in rivista

Tipo: Articolo in rivista

Titolo: Cortical metabolic arrangement during olfactory processing: Proposal for a 18F FDG PET/CT methodological approach

Anno di pubblicazione: 2014

Autori: Micarelli, Alessandro; Pagani, Marco; Chiaravalloti, Agostino; Bruno, Ernesto; Pavone, Isabella; Candidi, Matteo; Danieli, Roberta; Schillaci, Orazio; Alessandrini, Marco

Affiliazioni autori: Universita degli Studi di Roma Tor Vergata; Karolinska University Hospital; Universita degli Studi di Roma La Sapienza; Istituto Neurologico Mediterraneo Neuromed, Pozzilli, Istutito di Scienze e Tecnologie della Cognizione, CNR

Autori CNR:

  • MARCO PAGANI

Lingua: inglese

Abstract: The aim of this article is to investigate the cortical metabolic arrangements in olfactory processing by using 18F fluorodeoxyglucose (FDG) positron emission tomography/computed tomography. Twenty-six normosmic individuals (14 women and 12 men; mean age 46.710 years) were exposed to a neutral olfactory condition (NC) and, after 1 month, to a pure olfactory condition (OC) in a relatively ecological environment, that is, outside the scanner. All the subjects were injected with 185-210 megabecquerel of 18F FDG during both stimulations. Statistical parametric mapping version 2 was used in order to assess differences between NC and OC. As a result, we found a significant higher glucose consumption during OC in the cuneus, lingual, and parahippocampal gyri, mainly in the left hemisphere. During NC, our results show a relative higher glucose metabolism in the left superior, inferior, middle, medial frontal, and orbital gyri as well as in the anterior cingulate cortex. The present investigation, performed with a widely available functional imaging clinical tool, may help to better understand the neural responses associated to olfactory processing in healthy individuals and in patients with olfactory disorders by acquiring data in an ecologic, noise-free, and resting condition in which possible cerebral activations related to unwanted attentional processes might be avoided.

Lingua abstract: inglese

Pagine totali: 7

Rivista:

Medicine Williams & Wilkins Co.
Paese di pubblicazione: Stati Uniti d'America
Lingua: inglese
ISSN: 0025-7974

Numero volume: 93

Numero fascicolo: 19

DOI: 10.1097/MD.0000000000000103

Referee: Sė: Internazionale

Indicizzato da: Scopus [2-s2.0-84916234872]

Parole chiave:

  • FDG-PET
  • Olfactory Processing

URL: http://www.scopus.com/record/display.url?eid=2-s2.0-84916234872&origin=inward

Strutture CNR:

Moduli:

Allegati: 2014 MEDICINE Olfactory Processing FDG PET (application/pdf)

 
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