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Istituto di scienza dell'alimentazione

Torna all'elenco Contributi in rivista anno 2008

Contributo in rivista

Tipo: Articolo in rivista

Titolo: Evaluation of ovarian adhesion formation after laparoscopic ovarian drilling by second-look minilaparoscopy

Anno di pubblicazione: 2008

Autori: Mercorio F, Mercorio A, Di Spiezio Sardo A, Barba G, Pellicano M, Nappi C

Affiliazioni autori: Department of Gynaecology and Obstetrics, and Pathophysiology of Human Reproduction, University of Naples Federico II Insitute of Food Science, CNR

Autori CNR:

  • GIANVINCENZO BARBA

Lingua: inglese

Abstract: OBJECTIVE: To determine the incidence, site, and grade of ovarian adhesion formation after laparoscopic ovarian drilling (LOD) and analyze the association between the number of punctures made and the incidence and grade of adhesions, and evaluate the lateral distribution of the adhesions. DESIGN: Prospective clinical study. SETTING: University hospital endocrine and infertility center. PATIENT(S): Ninety-six anovulatory infertile women with polycystic ovarian syndrome (PCOS) treated with LOD. INTERVENTION(S): Women were randomized into two study groups of 48 women each, one treated with 6 punctures on the left ovary and 12 on the right, and the other treated with 6 punctures on the right ovary and 12 on the left. A short-term second-look minilaparoscopy was performed to evaluate postsurgical adhesion formation. MAIN OUTCOME MEASURE(S): [1] Evaluation of the incidence and grade (thin, dense, cohesive) of ovarian adhesions; [2] comparative analysis of the incidence and grade of ovarian adhesions between ovaries treated with 6 and 12 punctures; and [3] comparative analysis of the incidence and grade of ovarian adhesions between the two sides. RESULT(S): Adhesion formation was detected in 54 of the 90 women (60%) and in 83 of the 180 ovaries treated (46%). Dense adhesions were more likely to develop on the left ovaries to a statistically significant extent, and independently of the number of ovarian punctures performed (odds ratio [OR] = 4.34, 95% confidence interval [CI] = 1.72-10.94). Logistic regression analysis showed that the incidence of ovarian adhesions was independent of both number of punctures (OR = 1.05, 95% CI = 0.58-1.88) and side (OR = 1.37, 95% CI = 0.76-2.46). CONCLUSION(S): The incidence of ovarian adhesion formation after LOD was high, and their extent and severity was not influenced by the number of ovarian punctures; however, the left ovary appeared more prone to develop severe adhesions than the contralateral one.

Lingua abstract: inglese

Pagine da: 1229

Pagine a: 1233

Rivista:

Fertility and sterility American Society for Reproductive Medicine [etc.]
Paese di pubblicazione: Stati Uniti d'America
Lingua: inglese
ISSN: 0015-0282

Numero volume: 89

DOI: 10.1016/j.fertnstert.2007.05.009

Referee: Sė: Internazionale

Parole chiave:

  • Laparoscopic ovarian drilling
  • ovarian adhesions
  • polycystic ovarian syndrome
  • punctures
  • laterality

Strutture CNR:

Moduli:

 
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