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Istituto di scienza dell'alimentazione

Torna all'elenco Contributi in rivista anno 2011

Contributo in rivista

Tipo: Articolo in rivista

Titolo: Immunological evaluation of the alcohol-soluble protein fraction from Gluten-Free Grains in Relation to Celiac Disease

Anno di pubblicazione: 2011

Formato: Cartaceo

Autori: Bergamo P; Maurano F; Mazzarella G; Vocca I; Rivelli A; De Falco E; Gianfrani C; Rossi M.

Affiliazioni autori: Institute of Food Sciences, National Research Council, Avellino, Italy Gastroenterology Department, San G. Moscati Hospital, Avellino, Italy Department of Crop Systems, Forestry and Environmental Science, University

Autori CNR:

  • PAOLO BERGAMO
  • CARMELA GIANFRANI
  • FRANCESCO MAURANO
  • GIUSEPPE MAZZARELLA
  • MAURO ROSSI

Lingua: inglese

Abstract: Celiac disease (CD) is a gluten-sensitive enteropathy with an immune basis. We established the immune reactivity of the alcohol-soluble fraction from two minor cereals (tef and millet) and two pseudocereals (amaranth and quinoa) which are believed to be nontoxic based on taxonomy. Grains were examined in intestinal T-cell lines (iTCLs), cultures of duodenal explants from HLA-DQ21 CD patients and HLA-DQ8 transgenic mice for signs of activation. Our data indicated that tef, millet, amaranth, and quinoa did not show any immune crossreactivity toward wheat gliadin, and therefore confirming their safety in the diet of CD patients.

Pagine da: 1266

Pagine a: 1270

Rivista:

Molecular nutrition & food research Wiley-VCH-Verl..
Paese di pubblicazione: Germania
Lingua: inglese
ISSN: 1613-4125

Numero volume: 55

Numero fascicolo: 8

Strutture CNR:

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