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Istituto di scienza dell'alimentazione

Torna all'elenco Contributi in rivista anno 2006

Contributo in rivista

Tipo: Articolo in rivista

Titolo: Real-time contrast-enhanced specific ultrasound in staging and follow-up of splenic lymphomas.

Anno di pubblicazione: 2006

Formato: Elettronico

Autori: Tafuto S, Catalano O, Barba G, Sandomenico F, Lo bianco R, Tortoriello A, Formato R, Comella P, Siani A, Di Meo M, Iaffaioli RV, and Quattrin S.

Affiliazioni autori: 1 Department of Medical Oncology,S. Maria delle Grazie Hospital Pozzuoli, Italy; 2 Department of Radiology, National Cancer Institute, Naples,Italy, 3 Epidemiology and Population Genetics, Institute of Food Science, Avellino, Italy; 4 Department of Radiology, S. Maria delle Grazie Hospital Pozzuoli, Italy; 5 Department of Medical Oncology, National Cancer Institute, Naples. Italy

Autori CNR:


Lingua: inglese

Abstract: From January 2003 to April 2005 we studied 25 lymphoma patients (10 with HD, 4 with low-grade NHL, 6 with high-grade NHL and 5 with chronic lymphatic leukaemia; 14 men, 11 women, age range 28-79 years). After a baseline US study we rapidly injected 4.8 mL of the second-generation microbubble contrast agent SonoVue (Bracco, Italy). Contrast enhanced studies were carried out with the contrast-specific software named Contrast Tuned Imaging (Esaote, Italy) using a continuous, harmonic acquisition and a low acoustic pressure. The CS-US findings were correlated with results of standard tools, including CT, MRI, US follow up. CS-US revealed correctly 47 out of the 52 lesions identified by CT scan, in the absence of false positive findings (sensitivity = 90%; Specificity = 100%, in comparison to CT scan). Complete concordance in evaluating the lesion extension of the CS-US in respect to CT was 88%, while underestimate occurred in 9% and overestimate in 3% of cases. On the contrary, basic sonography defined correctly the dimensional alteration in 52% of the cases, underestimated in 35% and overestimated in 13%, thus showing significantly lower accuracy (chi-square = 30.0, p < 0.001). In our experience, CS-US was superior to conventional sonography even from a qualitative point of view.

Lingua abstract: inglese

Pagine da: 2224

Pagine a: 2229


Frontiers in bioscience Frontiers in Bioscience Publications,
Paese di pubblicazione: Stati Uniti d'America
Lingua: inglese
ISSN: 1093-9946

Numero volume: 11

Referee: Sė: Internazionale

Parole chiave:

  • Lymphomas
  • Tumor
  • Cancer
  • Lymph node
  • Contrast-Enhanced Specific Ultrasound
  • Staging

Strutture CNR:


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