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Istituto di scienza dell'alimentazione

Torna all'elenco Contributi in rivista anno 2004

Contributo in rivista

Tipo: Articolo in rivista

Titolo: Nutrition and prevention of ischemic stroke: present knowledge, limitations and future perspectives.

Anno di pubblicazione: 2004

Autori: Strazzullo P; Scalfi L; Branca F; Cairella G; Garbagnati F; Siani A; Barba G; Rubba P; Mancia G.

Affiliazioni autori: Department of Clinical and Experimental Medicine, Department of Food Science, Federico II University of Naples, National Institute for Research on Foods and Nutrition, Rome, Institute of Food Sciences, CNR, Avellino, and Department of Clinical Medicine, Prevention and Applied Biotechnologies, University of Milano-Bicocca, Monza, Italy

Autori CNR:

  • GIANVINCENZO BARBA
  • ALFONSO SIANI

Lingua: inglese

Abstract: Stroke, particularly ischemic stroke, has a major impact on public health due to its high incidence, prevalence and rate of subsequent disability in Italy as in most industrialised countries. Apart from age, many modifiable factors, such as hypertension, smoking, diabetes, dyslipidemia, obesity, physical inactivity, alcohol abuse and hyperhomocysteinemia, have been recognised as playing a role in the pathogenesis of this disease. While appropriate pharmacological therapy has proven effective in the prevention of stroke in particular categories of patients, most of the above mentioned predisposing conditions are amenable to be affected by nutrition. Unequivocal demonstration of a protective or adverse role of single foods and nutrients against the risk of stroke has been however difficult to achieve due to confounding by biological variability, methodological inadequacies in the assessment of individual nutritional habits and difficulty to carry out long-term randomised controlled trials in the nutritional area. Notwithstanding, in several cases, causal relationships could be inferred from case-control and cohort studies in the presence of plausible and reproducible associations, evidence of dose-dependent effects and consistency in the results of different studies. The aim of this paper was to review present knowledge and highlight limitations and future perspectives about the role of nutrition in the prevention of ischemic stroke.

Lingua abstract: inglese

Pagine da: 97

Pagine a: 114

Rivista:

NMCD. Nutrition Metabolism and Cardiovascular Diseases Medikal Press.
Paese di pubblicazione: Italia
Lingua: inglese
ISSN: 0939-4753

Numero volume: 14

Numero fascicolo: 2

DOI: 10.1016/S0939-4753(04)80017-6

Referee: Sė: Internazionale

Indicizzato da: ISI Web of Science (WOS) [000221966000007]

Parole chiave:

  • Nutrition
  • ischemic stroke
  • prevention
  • foods
  • nutrients.

Strutture CNR:

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