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Istituto di scienza dell'alimentazione

Torna all'elenco Contributi in rivista anno 2017

Contributo in rivista

Tipo: Rassegna della letteratura scientifica in rivista (Literature review)

Titolo: Antiobesity Effects of Anthocyanins in Preclinical and Clinical Studies

Anno di pubblicazione: 2017

Formato: Elettronico

Autori: Azzini, Elena; Giacometti, Jasminka; Russo, Gian Luigi

Affiliazioni autori: Council Agr Res & Econ CREA; Univ Rijeka; CNR

Autori CNR:

  • GIAN LUIGI RUSSO

Lingua: inglese

Abstract: The natural phytochemicals present in foods, including anthocyanins, might play a role in attenuating obesity by producing a decrease in weight and adipose tissue. This review focused on current knowledge about anthocyanins' role in obesity and its related comorbidities reported in animal models and humans. We summarized their target identification and mechanism of action through several pathways and their final effects on health and well-being. Into consideration of ongoing researches, we highlighted the following key points: a healthy relationship between anthocyanin supplementation and antiobesity effects suffers of the same pros and cons evidenced when the beneficial responses to other phytochemical treatments towards different degenerative diseases have been considered; the different dosage applied in animal versus clinical studies; the complex metabolism and biotransformation to which anthocyanins and phytochemicals are subjected in the intestine and tissues; the possibility that different components present in the supplemented mixtures can interact generating antagonistic, synergistic, or additive effects difficult to predict, and the difference between prevention and therapy. The evolution of the field must seriously consider the need to establish new and adequate cellular and animal models which may, in turn, allow the design of more efficient and prevention-targeted clinical studies.

Lingua abstract: inglese

Pagine da: 1

Pagine a: 14

Pagine totali: 11

Rivista:

Oxidative medicine and cellular longevity Landes Bioscience
Paese di pubblicazione: Stati Uniti d'America
Lingua: inglese
ISSN: 1942-0994

DOI: 10.1155/2017/2740364

Referee: Sė: Internazionale

Stato della pubblicazione: Published version

Indicizzato da: ISI Web of Science (WOS) [000405421900001]

Parole chiave:

  • obesity
  • anthocyanins

URL: https://www.hindawi.com/journals/omcl/2017/2740364/abs/

Strutture CNR:

 
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