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Contributo in rivista
Tipo: Articolo in rivista
Titolo: Prospective associations between dietary patterns and high sensitivity C-reactive protein in European children: the IDEFICS study
Anno di pubblicazione: 2018
Autori: González-Gil EM, Tognon G, Lissner L, Intemann T, Pala V, Galli C, Wolters M, Siani A, Veidebaum T, Michels N, Molnar D, Kaprio J, Kourides Y, Fraterman A, Iacoviello L, Picó C, Fernández-Alvira JM, Moreno Aznar LA; IDEFICS Consortium.
Affiliazioni autori: 1 GENUD (Growth, Exercise, NUtrition and Development) Research Group, Faculty of Health Sciences, Universidad de Zaragoza, C/ Pedro Cerbuna, 12, 50009, Zaragoza, Spain. firstname.lastname@example.org. 2 Instituto Agroalimentario de Aragón (IA2), Zaragoza, Spain. email@example.com. 3 Instituto de Investigación Sanitaria Aragón (IIS Aragón), Zaragoza, Spain. firstname.lastname@example.org. 4 Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBERObn), Madrid, Spain. email@example.com. 5 Section for Epidemiology and Social Medicine (EPSO), Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. 6 Leibniz Institute for Prevention Research and Epidemiology, Bremen, Germany. 7 Department of Preventive Medicine, Nutritional Epidemiology Unit, Fondazione IRCSS Istituto Nazionale dei Tumori, Milan, Italy. 8 Department of Pharmacological Sciences, University of Milan, Milan, Italy. 9 Unit of Epidemiology and Population Genetics, Institute of Food Sciences, National Research Council, Avellino, Italy. 10 National Institute for Health Development, Estonian Centre of Behavioral and Health Sciences, Tallinn, Estonia. 11 Department of Public Health, Ghent University, Ghent, Belgium. 12 Department of Paediatrics, Medical Faculty, University of Pécs, Pécs, Hungary. 13 Department of Public Health and Institute for Molecular Medicine FIMM, University of Helsinki, Helsinki, Finland. 14 Research and Education Institute of Child health, REF, Strovolos, Cyprus. 15 Laboratoriumsmedizin Dortmund, Eberhard & Partner, Dortmund, Germany. 16 IRCCS Istituto Neurologico Mediterraneo Neuromed, Pozzilli, Molise, Italy. 17 Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBERObn), Madrid, Spain. 18 Laboratory of Molecular Biology, Nutrition and Biotechnology, University of the Balearic Islands, Palma de Mallorca, Spain. 19 GENUD (Growth, Exercise, NUtrition and Development) Research Group, Faculty of Health Sciences, Universidad de Zaragoza, C/ Pedro Cerbuna, 12, 50009, Zaragoza, Spain. 20 Fundación Centro Nacional de Investigaciones Cardiovasculares (CNIC) Carlos III, Madrid, Spain. 21 Instituto Agroalimentario de Aragón (IA2), Zaragoza, Spain. 22 Instituto de Investigación Sanitaria Aragón (IIS Aragón), Zaragoza, Spain.
Abstract: Purpose This prospective study explores high sensitivity C-reactive protein (hs-CRP) levels in relation to dietary patterns at two time points in European children. Methods Out of the baseline sample of the IDEFICS study (n=16,228), 4020 children, aged 2-9 years at baseline, with available hs-CRP levels and valid data from a food frequency questionnaire (FFQ) at baseline (T0) and 2 years later (T1) were included. K-means clustering algorithm based on the similarities between relative food consumption frequencies of the FFQ was applied. hs-CRP was dichotomized according to sex-specific cutoff points. Multilevel logistic regression was performed to assess the relationship between dietary patterns and hs-CRP adjusting for covariates. Results Three consistent dietary patterns were found at T0 and T1: 'animal protein and refined carbohydrate', 'sweet and processed' and 'healthy'. Children allocated to the 'protein' and 'sweet and processed' clusters at both time points had significantly higher odds of being in the highest category of hs-CRP (OR 1.47; 95% CI 1.03-2.09 for 'animal protein and refined carbohydrate' and OR 1.44; 95% CI 1.08-1.92 for 'sweet and processed') compared to the 'healthy' cluster. The odds remained significantly higher for the 'sweet and processed' pattern (OR 1.39; 95% CI 1.05-1.84) when covariates were included.
Lingua abstract: inglese
Pagine da: 1397
Pagine a: 1407
Pagine totali: 11
European journal of nutrition
Numero volume: 57
Numero fascicolo: 4
Referee: Sì: Internazionale
Stato della pubblicazione: Published version
Indicizzato da: ISI Web of Science (WOS) 
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