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Istituto di scienza dell'alimentazione

Torna all'elenco Contributi in rivista anno 2017

Contributo in rivista

Tipo: Articolo in rivista

Titolo: Role of microRNAs in obesity and obesity-related diseases

Anno di pubblicazione: 2017

Formato: Elettronico

Autori: Iacomino G.; Siani A.

Affiliazioni autori: Institute of Food Sciences, CNR, Via Roma, 64, Avellino, 83100, , Italy

Autori CNR:

  • GIUSEPPE IACOMINO
  • ALFONSO SIANI

Lingua: inglese

Abstract: In recent years, the link between regulatory microRNAs (miRNAs) and diseases has been the object of intensive research. miRNAs have emerged as key mediators of metabolic processes, playing crucial roles in maintaining/altering physiological processes, including energy balance and metabolic homeostasis. Altered miRNAs expression has been reported in association with obesity, both in animal and human studies. Dysregulation of miRNAs may affect the status and functions of different tissues and organs, including the adipose tissue, pancreas, liver, and muscle, possibly contributing to metabolic abnormalities associated with obesity and obesity-related diseases. More recently, the discovery of circulating miRNAs easily detectable in plasma and other body fluids has emphasized their potential as both endocrine signaling molecules and disease indicators. In this review, the status of current research on the role of miRNAs in obesity and related metabolic abnormalities is summarized and discussed.

Lingua abstract: inglese

Rivista:

Genes & nutrition Springer
Paese di pubblicazione: Germania
Lingua: inglese
ISSN: 1555-8932

Numero volume: 12

DOI: 10.1186/s12263-017-0577-z

Referee: Sė: Internazionale

Stato della pubblicazione: Published version

Indicizzato da: Scopus [2-s2.0-85029867917]

Parole chiave:

  • microRNA
  • Obesity
  • metabolic diseases

URL: http://www.scopus.com/record/display.url?eid=2-s2.0-85029867917&origin=inward

Strutture CNR:

 
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