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Istituto di scienza dell'alimentazione

Torna all'elenco Contributi in rivista anno 2016

Contributo in rivista

Tipo: Articolo in rivista

Titolo: Vitamin D status and risk for malignant cutaneous melanoma: recent advances

Anno di pubblicazione: 2016

Formato: Elettronico Cartaceo

Autori: Maria Neve Ombra, Panagiotis Paliogiannis, Valentina Doneddu, Maria Cristina Sini, Maria Colombino, Carla Rozzo, Ignazio Stanganelli, Francesco Tanda, Antonio Cossu, Giuseppe Palmieri

Affiliazioni autori: Institute of Food Sciences, National Research Council (CNR), Via Roma 64, 83100, Avellino. Department of Surgical, Microsurgical and Medical Sciences, University of Sassari, Viale San Pietro 43, 07100, Sassari, Italy. Institute of Biomolecular Chemistry, National Research Council (CNR), Cancer Genetics Unit, Traversa La Crucca 3, 07040, Sassari, Italy. Skin Cancer Unit, Istituto Scientifico Romagnolo per lo studio e la cura dei tumori, Via Piero Maroncelli 40, 47014, Meldola, Italy

Autori CNR:

  • MARIA COLOMBINO
  • MARIA NEVE OMBRA
  • GIUSEPPE PALMIERI
  • CARLA MARIA ROZZO
  • MARIA CRISTINA SINI

Lingua: inglese

Abstract: Cutaneous malignant melanoma, whose incidence is steadily increasing worldwide, is the result of complex interactions between individual genetic factors and environmental risk factors. Ultraviolet radiation represents the most important environmental risk factor for the development of skin cancers, including melanoma. Sun exposure and early sunburn during the childhood is the principal cause of cutaneous melanoma insurgence in adult, with a double risk relative to non-exposed population. Consequently, ultraviolet protection has been long recognized as an important measure to prevent such a malignancy. Biological and epidemiological data suggest that vitamin D status could affect cancer risk and play a role in cancer prevention by exerting anti-proliferative effects. Solar radiations are critical for vitamin D synthesis in humans; however, uncontrolled and intensive sun exposure is dangerous to skin health and may contribute to the development of cutaneous malignant melanoma. A correct balance between sun protection and exposure is thus advocated. Additional research is required to confirm a preventive role of vitamin D on melanoma incidence or a healthful influence on patient outcome.

Lingua abstract: inglese

Rivista:

European journal of cancer prevention Rapid Communications of Oxford,
Paese di pubblicazione: Regno Unito
Lingua: inglese
ISSN: 0959-8278

Stato della pubblicazione: Preprint

Parole chiave:

  • Melanoma
  • Vitamina D
  • Prevenzione oncologica

Strutture CNR:

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